Successful treatment with cyclosporine and guselkumab for pityriasis rubra pilaris

被引：10

作者：

Nishimura, Mai ^{[1
]}

Kondo, Makoto ^{[1
]}

Habe, Koji ^{[1
]}

Hayashi, Akinobu ^{[2
]}

Yamanaka, Keiichi ^{[1
]}

机构：

[1] Mie Univ, Dept Dermatol, Grad Sch Med, 2-174 Edobashi, Tsu, Mie 5148507, Japan

[2] Mie Univ, Dept Oncol Pathol, Grad Sch Med, Tsu, Mie, Japan

来源：

CLINICAL CASE REPORTS | 2022年 / 10卷 / 10期

关键词：

cyclosporine; guselkumab; IL-23p19; pityriasis rubra pilaris;

D O I：

10.1002/ccr3.6413

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A man with pityriasis rubra pilaris (PRP) showed no improvement in skin symptoms despite treatment with several drugs. The patient was diagnosed as having type 1 PRP. Combination therapy with cyclosporine and guselkumab improved his skin condition. Here, we propose a novel therapeutic strategy for intractable PRP.

引用

页数：4

共 7 条

[1] Rapid response of pityriasis rubra pilaris with psoriasis overlap to secukinumab [J].

Cole, D. ;

Mohammad, T. ;

Lim, H. .

BRITISH JOURNAL OF DERMATOLOGY, 2019, 181 (06) :1331-1332

[2] Successful Treatment of Pityriasis Rubra Pilaris with Ixekizumab [J].

Hanfstingl, Kathrin ;

Pekar-Lukacs, Agnes ;

Motz, Reinhard ;

Guenova, Emmanuella ;

Hoetzenecker, Wolfram .

CASE REPORTS IN DERMATOLOGY, 2018, 10 (02) :97-100

[3] IL-23 induces regulatory T cell plasticity with implications for inflammatory skin diseases [J].

Kannan, Arun K. ;

Su, Zhi ;

Gauvin, Donna M. ;

Paulsboe, Stephanie E. ;

Duggan, Ryan ;

Lasko, Loren M. ;

Honore, Prisca ;

Kort, Michael E. ;

McGaraughty, Steve P. ;

Scott, Victoria E. ;

Gauld, Stephen B. .

SCIENTIFIC REPORTS, 2019, 9 (1)

[4] Case of pityriasis rubra pilaris progressed to generalized erythroderma following blockade of interleukin-17A, but improved after blockade of interleukin-12/23 p40 [J].

Matsuda, Tomoko ;

Yamazaki, Fumikazu ;

Ueda-Hayakawa, Ikuko ;

Kambe, Naotomo ;

Okamoto, Hiroyuki .

JOURNAL OF DERMATOLOGY, 2019, 46 (01) :70-72

[5] Epidemiologic, Clinicopathologic, Diagnostic, and Management Challenges of Pityriasis Rubra Pilaris A Case Series of 100 Patients [J].

Ross, Nicholas A. ;

Chung, Hye-Jin ;

Li, Qiaoli ;

Andrews, Jonathan P. ;

Keller, Matthew S. ;

Uitto, Jouni .

JAMA DERMATOLOGY, 2016, 152 (06) :670-675

[6]

Shibata TMJ., 2019, RINSHO DERMA, V61, P611

[7] A Review on Pityriasis Rubra Pilaris [J].

Wang, Dingyuan ;

Chong, Vanessa Cui-Lian ;

Chong, Wei-Sheng ;

Oon, Hazel H. .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2018, 19 (03) :377-390

← 1 →