Pesticide residues in human breast milk: Risk assessment for infants from Punjab, India

被引:61
作者
Bedi, J. S. [1 ]
Gill, J. P. S. [1 ]
Aulakh, R. S. [1 ]
Kaur, P. [1 ]
Sharma, A. [1 ]
Pooni, P. A. [2 ]
机构
[1] Guru Angad Dev Vet & Anim Sci Univ, Sch Publ Hlth & Zoonoses, Ludhiana 141004, Punjab, India
[2] Dayanand Med Coll & Hosp, Ludhiana 141001, Punjab, India
关键词
DDTs; HCHs; Human breast milk; Risk assessment; Infants; PERSISTENT ORGANOCHLORINE PESTICIDES; POLYBROMINATED DIPHENYL ETHERS; POLYCHLORINATED-BIPHENYLS; CHLORINATED PESTICIDES; CONTAMINATION; EXPOSURE; DDT; MOTHERS; ACCUMULATION; WOMEN;
D O I
10.1016/j.scitotenv.2013.06.066
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Punjab state in India is an agrarian society, where agriculture is the lifeline of farming community. To keep pace with increasing demands of food for growing population the indiscriminate use of pesticides has led to the contamination of environment and food commodities in this region. Analysis of human breast milk samples (n = 53) for pesticide residues revealed the presence of beta-, gamma-HCH, p,p' DDD, p,p' DDE, p,p' DDT and endrin with mean concentration of 97.9, 101.7, 239.8, 1574.1, 1003 and 90.7 ng g(-1) lipid wt., respectively. In addition, occurrence of beta-endosulfan, endosulfan sulphate, cypermethrin and chlorpyrifos in this study have also been reported for the first time in human breast milk in Punjab, India. With increase in parity, HCH and DDT residue burden in donor's milk decreased. Although levels of HCH and DDT residues in breast milk samples have decreased significantly, yet estimated daily intake values for DDT are higher than the FAO/WHO permissible tolerable daily intake values for few infants. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:720 / 726
页数:7
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