Wnt signalling in lung development and diseases

被引：178
作者：
Pongracz, JE [1 ]
Stockley, RA
机构：
[1] Univ Pecs, Dept Immunol & Biotechnol, Pecs, Hungary
[2] Univ Birmingham, Inst Biomed Res, Birmingham, W Midlands, England
[3] Univ Birmingham, Dept Med, Birmingham, W Midlands, England
来源：
RESPIRATORY RESEARCH | 2006年 / 7卷 / 1期
关键词：
D O I：
10.1186/1465-9921-7-15
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
There are several signalling pathways involved in lung organogenesis including Notch, TGF beta/BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge. In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases.
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