The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study

被引：23

作者：

Prieto-Alhambra, D. ^{[1
,2
,3
,4
]}

Moral-Cuesta, D. ^{[5
]}

Palmer, A. ^{[6
]}

Aguado-Maestro, I. ^{[7
]}

Bravo Bardaji, M. F. ^{[8
]}

Branas, F. ^{[9
]}

Adrados Bueno, G. ^{[10
]}

Caeiro-Rey, J. R. ^{[11
]}

Andres Cano, I. ^{[12
]}

Barres-Carsi, M. ^{[13
]}

Gracia Delgado, L. ^{[14
]}

Salomo-Domenech, M. ^{[15
]}

Etxebarria-Foronda, I. ^{[16
]}

Ferrer, B. Llado ^{[17
]}

Mills, S. ^{[18
]}

Ezquerra Herrando, L. ^{[19
]}

Mifsut, D. ^{[20
]}

Evangelista, L. D. R. ^{[21
]}

Nogues, X. ^{[22
]}

Perez-Coto, I. ^{[23
]}

Martinez-Iniguez Blasco, J. ^{[24
]}

Martin-Hernandez, C. ^{[25
]}

Kessel, H. ^{[26
]}

Teixidor Serra, J. ^{[27
]}

Rodriguez Solis, J. ^{[28
]}

Torregrosa Suau, O. ^{[29
]}

Vaquero-Cervino, E. ^{[30
]}

Pablos Hernandez, C. ^{[31
]}

Rodriguez Manas, L. ^{[32
]}

Herrera, A. ^{[33
]}

Diez-Perez, A. ^{[34
]}

机构：

[1] Univ Autonoma Barcelona, GREMPAL, Res Grp, CIBERFES,IDIAP Jordi Gol, Av Gran Via Corts Catalanes 587, Barcelona 08007, Spain

[2] Inst Salud Carlos III, Av Gran Via Corts Catalanes 587, Barcelona 08007, Spain

[3] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Musculoskeletal Pharmaco & Device Epidemiol, Ctr Stat Med,Botnar Res Ctr, Windmill Rd, Oxford OX3 7LD, England

[4] Univ Autonoma Barcelona, Musculoskeletal Res Unit, IMIM Parc Salut Mar, CIBERFES, Doctor Aiguader 88, Barcelona 08003, Spain

[5] Hosp Univ La Paz, Geriatr Unit, Paseo Castellana 261, Madrid 28046, Spain

[6] Nuffield Orthoped Ctr, Traumatol & Orthopaed Unit, Windmill Rd, Oxford OX3 7HE, England

[7] Hosp Univ Rio Hortega, Calle Dulzaina 2, Valladolid 47012, Spain

[8] Hosp Reg Univ Malaga, Ave Carlos Haya S-N, Malaga 29010, Spain

[9] Hosp Univ Infanta Leonor, Geriatr Unit, Gran Via Este 80, Madrid 28031, Spain

[10] Hosp Infanta Cristina, Internal Med Unit, Ave Elvas S-N, Badajoz 06080, Spain

[11] Complejo Hosp Univ Santiago de Compostela, Traumatol & Orthopaed Unit, Rua Choupana S-N, Santiago De Compostela 15706, A Coruna, Spain

[12] Hosp Puerta Mar, Ave Ana Viya 21, Cadiz 11009, Spain

[13] Hosp Univ & Politecn La Fe, Av Fernando Abril Martorell 106, Valencia 46026, Spain

[14] Hosp Univ Reina Sofia Cordoba, Av Menendez Pidal, Cordoba 14004, Spain

[15] Corp Sanitaria Univ Parc Tauli, Parc Tauli 1, Barcelona 08208, Spain

[16] Alto Deba Hosp, Dept Orthopaed, Arrasate Mondragon, Gipuzkoa, Spain

[17] Hosp Son Llatzer, Carretera Manacor,PQ 4 Son Ferriol, Palma De Mallorca 07198, Spain

[18] Hosp Univ La Paz, Traumatol & Orthopaed Unit, Paseo Castellana 261, Madrid 28046, Spain

[19] Hosp Clin Univ Lozano Blesa, FEA Traumatol & Orthopaed Unit, Ave San Juan Bosco 15, Zaragoza 50009, Spain

[20] Hosp Clin Valencia, Av Blasco Ibanez 17, Valencia 46010, Spain

[21] Hosp Univ Severo Ochoa, Geriatr Unit, Ave Orellana S-N, Madrid 28911, Spain

[22] Univ Autonoma Barcelona, Dept Internal Med, CIBER FES ISCIII, IMIM Hosp Mar Med Res, Barcelona, Spain

[23] Hosp Univ San Agustin, Camino Heros 6, Aviles 33401, Asturias, Spain

[24] Hosp San Pedro, Calle Piqueras 98, Logrono 26006, La Rioja, Spain

[25] Hosp Univ Miguel Servet, IIS Aragon, Paseo Isabel Catolica 1-3, Zaragoza 50009, Spain

[26] Complejo Hosp Torrecardenas, Geriatr Care Unit, Calle Hermandad Donantes Sangre, Almeria 04009, Spain

[27] Hosp Univ Vall de Hebron, Passeig Vall dHebron 119-129, Barcelona 08035, Spain

[28] Hosp Univ Guadalajara, Geriatr Unit, Calle Donante Sangre S-N, Guadalajara 19002, Spain

[29] Hosp Gen Univ Elx, Bone Metab Unit, Internal Med Unit, Carrer Almazara 11, Alicante 03203, Spain

[30] Complejo Hosp Pontevedra, Av Montecelo 0, Casas Novas 36164, Pontevedra, Spain

[31] Hosp Salamanca, Geriatr Unit, Paseo San Vicente 139, Salamanca 37007, Spain

[32] Hosp Univ Getafe, Geriatr Unit, Carr Madrid Toledo,Km 12,500, Madrid 28905, Spain

[33] Univ Zaragoza, Aragon Hlth Res Inst, Dept Surg, Zaragoza, Spain

[34] Univ Autonoma Barcelona, Musculoskeletal Res Unit, IMIM Parc Salut Mar, CIBERFES, Doctor Aiguader 88, Barcelona 08003, Spain

来源：

ARCHIVES OF OSTEOPOROSIS | 2019年 / 14卷 / 01期

关键词：

Fragility hip fracture; Osteoporosis; Registries; Quality of life; UNITED-KINGDOM; MORTALITY; BURDEN; COSTS;

D O I：

10.1007/s11657-019-0607-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

PurposeThe medical morbidity and mortality associated with neck of femur fractures is well-documented, whereas there is limited data for patient-reported outcomes. The aim of this study was to characterize the impact of neck of femur fractures on activities of daily living and patient-reported health-related quality of life.MethodsDesign and participants: Multicentric prospective cohort study. Consecutive sample patients with fragility hip fracture over 50years old admitted in 48 hospitals in Spain.Outcomes: daily living activity function (Barthel Index) and health-related quality of life (EQ-5D) pre-fracture, admission to hospital and at 1- and 4-month follow-up post-fracture.Statistics: Barthel and EQ-5D over time are described as mean (SD) and median (interquartile range).ResultsA total of 997 patients were recruited at baseline with 4-month outcomes available for, and 856 patients (89.5%). Barthel Index fell from 78.77 (23.75) at baseline to 43.62 (19.86) on admission to hospital with the fracture. Scores partially recovered to 54.89 (25.40) and 64.09 (21.35) at 1- and 4-month post-fracture, respectively. EQ-5D fell from a median of 0.75 (0.47-0.91) to -0.01 (-0.03 to 0.51) on admission. Partial recovery was observed again to (0.51 (-0.06 to 0.67)) and (0.60 (0.10 to 0.80)) at 1- and 4-month post-fracture, respectively.ConclusionsHip fracture results in a large decline in the ability to perform activities of daily living and patient-reported health-related quality of life with only partial recovery amongst survivors 4-month post-fracture.

引用

页数：5

共 16 条

[1] A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states [J].

Badia, X ;

Roset, M ;

Herdman, M ;

Kind, P .

MEDICAL DECISION MAKING, 2001, 21 (01) :7-16

[2] The International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)-quality of life during the first 4 months after fracture [J].

Borgstrom, F. ;

Lekander, I. ;

Ivergard, M. ;

Strom, O. ;

Svedbom, A. ;

Alekna, V. ;

Bianchi, M. L. ;

Clark, P. ;

Curiel, M. D. ;

Dimai, H. P. ;

Jurisson, M. ;

Kallikorm, R. ;

Lesnyak, O. ;

McCloskey, E. ;

Nassonov, E. ;

Sanders, K. M. ;

Silverman, S. ;

Tamulaitiene, M. ;

Thomas, T. ;

Tosteson, A. N. A. ;

Jonsson, B. ;

Kanis, J. A. .

OSTEOPOROSIS INTERNATIONAL, 2013, 24 (03) :811-823

[3]

Collin C, 1988, Int Disabil Stud, V10, P61

[4] HIP-FRACTURES IN THE ELDERLY - A WORLDWIDE PROJECTION [J].

COOPER, C ;

CAMPION, G ;

MELTON, LJ .

OSTEOPOROSIS INTERNATIONAL, 1992, 2 (06) :285-289

[5] World Hip Trauma Evaluation (WHiTE): framework for embedded comprehensive cohort studies [J].

Costa, Matthew L. ;

Griffin, Xavier L. ;

Achten, Juul ;

Metcalfe, David ;

Judge, Andrew ;

Pinedo-Villanueva, Rafael ;

Parsons, Nicholas .

BMJ OPEN, 2016, 6 (10)

[6] Quality of life following hip fractures: results from the Norwegian hip fracture register [J].

Gjertsen, Jan-Erik ;

Baste, Valborg ;

Fevang, Jonas M. ;

Furnes, Ove ;

Engesaeter, Lars Birger .

BMC MUSCULOSKELETAL DISORDERS, 2016, 17

[7] Recovery of health-related quality of life in a United Kingdom hip fracture population [J].

Griffin, X. L. ;

Parsons, N. ;

Achten, J. ;

Fernandez, M. ;

Costa, M. L. .

BONE & JOINT JOURNAL, 2015, 97B (03) :372-382

[8] The burden of osteoporotic hip fractures in Portugal: costs, health related quality of life and mortality [J].

Marques, A. ;

Lourenco, O. ;

da Silva, J. A. P. .

OSTEOPOROSIS INTERNATIONAL, 2015, 26 (11) :2623-2630

[9] Factors associated with the course of health-related quality of life after a hip fracture [J].

Moerman, Sophie ;

Vochteloo, Anne J. H. ;

Tuinebreijer, Wim E. ;

Maier, Andrea B. ;

Mathijssen, Nina M. C. ;

Nelissen, Rob G. H. H. .

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 2016, 136 (07) :935-943

[10]

Pedersen AB, 2017, EPIDEMIOLOGY, V28, P898, DOI [10.1097/EDE.0000000000000729, 10.1097/ede.0000000000000729]

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