The newly emerged SARS-Like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease

被引：131
作者：
Ren, Zhilin [1 ,2 ,3 ,4 ]
Yan, Liming [1 ,2 ]
Zhang, Ning [6 ]
Guo, Yu [3 ,4 ]
Yang, Cheng [3 ,4 ,6 ]
Lou, Zhiyong [1 ,2 ]
Rao, Zihe [1 ,2 ,3 ,4 ,5 ,6 ]
机构：
[1] Nankai Univ, Coll Pharm, Tianjin 300071, Peoples R China
[2] Nankai Univ, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China
[3] Tsinghua Univ, Struct Biol Lab, Sch Med & Life Sci, Beijing 100084, Peoples R China
[4] Tsinghua Univ, MOE Lab Prot Sci, Sch Med & Life Sci, Beijing 100084, Peoples R China
[5] Chinese Acad Sci, Inst Biophys, Natl Lab Macromol, Beijing 100101, Peoples R China
[6] Tianjin Joint Acad Biomed & Technol, Emerging Infect Dis Program, High Throughput Mol Drug Discovery Ctr, Tianjin 300457, Peoples R China
来源：
PROTEIN & CELL | 2013年 / 4卷 / 04期
基金：
中国国家自然科学基金;
关键词：
MAIN PROTEASE; DESIGN;
D O I：
10.1007/s13238-013-2841-3
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：248 / 250
页数：3
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