Role of Ca2+ and transmitters of the sympathetic nervous system in transduction of stress signal in cardiomyocytes

被引:0
|
作者
Shemarova, I. V. [1 ]
Nesterov, V. P. [1 ]
机构
[1] Russian Acad Sci, Sechenov Inst Evolutionary Physiol & Biochem, St Petersburg 196140, Russia
基金
俄罗斯基础研究基金会;
关键词
D O I
10.1134/S0022093006020013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review summarizes current concepts of the role of Ca2+ and neurotransmitters of the sympathetic nervous system in transduction of stress signals leading to apoptosis or cell hypertrophy of cardiomyocytes. A particular attention is paid to consideration of contribution of MAP-kinases (mitogen-activated protein kinases) to transduction of stress signals coming into cardiomyocytes through mechanism of interaction of adrenoreceptors with ligands.
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页码:117 / 127
页数:11
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