Validation of plasma-derived small extracellular vesicles as cancer biomarkers

被引：18
|
作者：
Whiteside, Theresa L. [1 ,2 ,3 ,4 ]
机构：
[1] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA 15260 USA
[2] Univ Pittsburgh, Sch Med, Dept Immunol, Pittsburgh, PA 15260 USA
[3] Univ Pittsburgh, Sch Med, Dept Otolaryngol, Pittsburgh, PA 15260 USA
[4] UPMC Hillman Canc Ctr, Pittsburgh, PA 15260 USA
来源：
NATURE REVIEWS CLINICAL ONCOLOGY | 2020年 / 17卷 / 12期
关键词：
EXOSOMES;
D O I：
10.1038/s41571-020-00433-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A role for extracellular vesicles and particles (EVPs) as cancer biomarkers has been elusive. A mass spectrometry-based comparative analysis of EVPs from individuals with or without cancer has now enabled the identification of tumour-associated protein profiles in EVPs in plasma and paired tumour tissues, validating the role of EVPs as a novel liquid biopsy approach in cancer diagnosis.
引用
收藏
页码：719 / 720
页数：2
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