Electrochemical sensor and biosensor platforms based on advanced nanomaterials for biological and biomedical applications

被引:677
作者
Maduraiveeran, Govindhan [1 ,2 ]
Sasidharan, Manickam [1 ,2 ]
Ganesan, Vellaichamy [3 ]
机构
[1] SRM Inst Sci & Technol, Res Inst, Madras 603203, Tamil Nadu, India
[2] SRM Inst Sci & Technol, Dept Chem, Madras 603203, Tamil Nadu, India
[3] Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 221005, Uttar Pradesh, India
关键词
Nanomaterials; Electrochemical analysis; Biosensor; in vivo and in vitro analysis; Biomolecules; Biology; Biotechnology; Biomedicine; REDUCED GRAPHENE OXIDE; GLASSY-CARBON ELECTRODE; MOLECULARLY IMPRINTED POLYMER; GOLD NANOPARTICLES; SILVER NANOPARTICLES; ASCORBIC-ACID; PALLADIUM NANOPARTICLES; SENSING PLATFORM; NITRIC-OXIDE; URIC-ACID;
D O I
10.1016/j.bios.2017.12.031
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Introduction of novel functional nanomaterials and analytical technologies signify a foremost possibility for the advance of electrochemical sensor and biosensor platforms/devices for a broad series of applications including biological, biomedical, biotechnological, clinical and medical diagnostics, environmental and health monitoring, and food industries. The design of sensitive and selective electrochemical biological sensor platforms are accomplished conceivably by offering new surface modifications, microfabrication techniques, and diverse nanomaterials with unique properties for in vivo and in vitro medical analysis via relating a sensibly planned electrode/solution interface. The advantageous attributes such as low-cost, miniaturization, energy efficient, easy fabrication, online monitoring, and the simultaneous sensing capability are the driving force towards continued growth of electrochemical biosensing platforms, which have fascinated the interdisciplinary research arenas spanning chemistry, material science, biological science, and medical industries. The electrochemical biosensor platforms have potential applications in the early-stage detection and diagnosis of disease as stout and tunable diagnostic and therapeutic systems. The key aim of this review is to emphasize the newest development in the design of sensing and biosensing platforms based on functional nanomaterials for biological and biomedical applications. High sensitivity and selectivity, fast response, and excellent durability in biological media are all critical aspects which will also be wisely addressed. Potential applications of electrochemical sensor and biosensor platforms based on advanced functional nanomaterials for neuroscience diagnostics, clinical, point-of-care diagnostics and medical industries are also concisely presented.
引用
收藏
页码:113 / 129
页数:17
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