Can intravesical bacillus Calmette-Guerin reduce recurrence in patients with non-muscle invasive bladder cancer? An update and cumulative meta-analysis

被引：10
作者：
Pan, Jiangang [1 ]
Liu, Mo [2 ]
Zhou, Xing [1 ]
机构：
[1] Guangzhou Med Univ, Affiliated Hosp 2, Guangzhou 510260, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510120, Guangdong, Peoples R China
来源：
FRONTIERS OF MEDICINE | 2014年 / 8卷 / 02期
关键词：
non-muscle invasive bladder cancer; bacillus Calmette-Guerin (BCG); meta-analysis;
D O I：
10.1007/s11684-014-0328-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Approximately 70% of newly diagnosed bladder tumors are non-muscle invasive bladder cancer (NMIBC). NMIBC accounts for approximately 80% of total bladder cancer cases. Bacillus Calmette-Guerin (BCG) instillation and maintenance is considered as the standard adjuvant treatment for superficial bladder cancer. A number of randomized studies have focused on the benefit of maintenance therapy following initial BCG induction. To provide further insights into the effect of intravesical instillation on recurrence in patients with NMIBC, we analyzed this relationship by conducting an updated detailed meta-analysis. Evidence suggested that adjuvant intravesical BCG with maintenance treatment is significantly effective for the prophylaxis of tumor recurrence in patients with NMIBC.
引用
收藏
页码：241 / 249
页数：9
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