Effect of Methotrexate is Changed under Conditions of High Temperature of Ontogenesis as Exemplified byDrosophila melanogaster

被引：0

作者：

Antosyuk, O. N. ^{[1
]}

Suvorova, A. D. ^{[1
]}

机构：

[1] Ural Fed Univ, Ekaterinburg, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2020年 / 169卷 / 03期

关键词：

methotrexate; morphometric analysis; vestigial; Drosophila melanogaster; asynapsis;

D O I：

10.1007/s10517-020-04889-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Changes in the effect of methotrexate (400 mu g/kg nutrient medium) combined with high temperature (28 degrees C) of ontogenesis were studied on two hybrid lines ofDrosophila melanogasterheterozygous by thevestigialgene that underwent long-term target selection for cutting injury of the wing. Changes in the wing shape, mortality rate, and morphology of polytene chromosomes were studied.

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页码：369 / 372

页数：4

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