Synthesis and antibacterial activity of water-soluble chitin derivatives

被引：0

作者：

Kim, CH ^{[1
]}

Kim, SY ^{[1
]}

Choi, KS ^{[1
]}

机构：

[1] HANYANG UNIV,COLL ENGN,DEPT IND CHEM,SEOUL 133791,SOUTH KOREA

来源：

POLYMERS FOR ADVANCED TECHNOLOGIES | 1997年 / 8卷 / 05期

关键词：

diethylaminoethyl chitin; diethylaminoethyl chitosan; triethylaminoethyl chitin; antibacterial activity; enzymatic hydrolysis;

D O I：

10.1002/(SICI)1099-1581(199705)8:5<319::AID-PAT645>3.3.CO;2-7

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Diethylaminoethyl-chitin (DEAE-chitin) was synthesized by introducing DEAE groups onto the C(6)-OH in chitin. DEAE-chitin was N-deacetylated by heating in aqueous 10% sodium hydroxide containing sodium borohydride to prepare the diethylaminoethyl-chitosan (DEAE-chitosan). In addition, DEAE-chitin was quaternized with ethyl halide to produce triethylaminoethyl-chitin (TEAE-chitin). Their antibacterial activities were evaluated by using colony count against staphylococcus aureus and E.scherichia coli by means of shake flask method. The antibacterial activity was found to increase in order of DEAE-chitin, DEAE-chitosan, TEAE-chitin. DEAE-chitin was hydrolyzed by enzymes to investigate the effect of molecular weight on its antibacterial activities. The antibacterial activity was dependent on the structure, particularly on the molecular weight of chitin derivatives. (C) 1997 by John Wiley & Sons, Ltd.

引用

页码：319 / 325

页数：7

共 50 条

[1] New water-soluble derivatives of chitin and their based nanoparticles: Antibacterial and catalytic activity
Kritchenkov, Andreii S.
Kletskov, Alexey, V
Egorov, Anton R.
Kurliuk, Aleh, V
Rubanik, Vasilii V.
Rubanik, Vasilii V., Jr.
Khrustalev, Victor N.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 163 : 2005 - 2012
[2] Preparation of water-soluble chitosan derivatives and their antibacterial activity
Xie, WM
Xu, PX
Wang, W
Liu, Q
JOURNAL OF APPLIED POLYMER SCIENCE, 2002, 85 (07) : 1357 - 1361
[3] Synthesis and Antibacterial Activity of Chitin Tetrazole Derivatives
A. S. Kritchenkov
N. A. Lipkan
A. V. Kurliuk
T. V. Shakola
A. R. Egorov
O. V. Volkova
T. V. Meledina
E. P. Suchkova
L. A. Zabodalova
A. P. Dysin
Pharmaceutical Chemistry Journal, 2020, 54 : 138 - 141
[4] Synthesis and Antibacterial Activity of Chitin Tetrazole Derivatives
Kritchenkov, A. S.
Lipkan, N. A.
Kurliuk, A., V
Shakola, T., V
Egorov, A. R.
Volkova, O. V.
Meledina, T., V
Suchkova, E. P.
Zabodalova, L. A.
Dysin, A. P.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2020, 54 (02) : 138 - 141
[5] Synthesis and characterization of water-soluble chitosan derivate and its antibacterial activity
Xie, Yajun
Liu, Xiaofei
Chen, Qiang
CARBOHYDRATE POLYMERS, 2007, 69 (01) : 142 - 147
[6] Antibacterial Characteristics and Activity of Water-Soluble Chitosan Derivatives Prepared by the Maillard Reaction
Chung, Ying-Chien
Yeh, Jan-Ying
Tsai, Cheng-Fang
MOLECULES, 2011, 16 (10): : 8504 - 8514
[7] Preparation and antibacterial activity of a water-soluble chitosan derivative
Xie, WM
Xu, PX
Wang, W
Liu, Q
CARBOHYDRATE POLYMERS, 2002, 50 (01) : 35 - 40
[8] Carboxymethyl chitin and chitosan derivatives: Synthesis, characterization and antibacterial activity
Islam, Md. Monarul
Islam, Rashedul
Hassan, S. M. Mahmudul
Karim, Md. Rezaul
Rahman, Mohammad Mahbubur
Rahman, Shofiur
Hossain, Md. Nur
Islam, Dipa
Shaikh, Md. Aftab Ali
Georghiou, Paris E.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS, 2023, 5
[9] Synthesis and Antibacterial Activity of Hybrid Supramolecular Complexes Based on Tetracycline/Doxycycline and Water-Soluble C60-Fullerene Derivatives
Zhilenkov, A. V.
Khakina, E. A.
Troshin, P. A.
Inchagova, K. S.
Deryabin, D. G.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2017, 50 (10) : 637 - 641
[10] Synthesis and Antibacterial Activity of Hybrid Supramolecular Complexes Based on Tetracycline/Doxycycline and Water-Soluble C60-Fullerene Derivatives
A. V. Zhilenkov
E. A. Khakina
P. A. Troshin
K. S. Inchagova
D. G. Deryabin
Pharmaceutical Chemistry Journal, 2017, 50 : 637 - 641

← 1 2 3 4 5 →