House Dust Mite Sensitisation as a Risk Factor for Exacerbation of Asthma in the Fall

被引：0

作者：

Kim, H. H. ^{[1
]}

Choi, S. J. ^{[2
]}

Won, S. ^{[1
]}

Kim, H. S. ^{[1
]}

Chun, Y. H. ^{[1
]}

Yoon, J. S. ^{[1
]}

Kim, J. T. ^{[1
]}

机构：

[1] Catholic Univ Korea, Coll Med, Dept Pediat, Seoul, South Korea

[2] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pediat,Childrens Hosp, Seoul, South Korea

来源：

HONG KONG JOURNAL OF PAEDIATRICS | 2016年 / 21卷 / 04期

关键词：

Asthma; Child; Cytokines; House dust mite; Seasons; SEPTEMBER EPIDEMIC; CHILDREN; EXPOSURE; ALLERGEN; CHILDHOOD; WEATHER;

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Purpose: Exposure and sensitisation to house dust mites (HDMs) are known to aggravate asthma. We aimed to determine whether sensitisation to HDM acts as a risk factor for asthma exacerbation in fall and we also investigated whether asthma exacerbation in the fall had any distinctive features by comparing various cytokines and chemokines with other seasons. Method: We measured the levels of total immunoglobulin E (IgE), HDM-specific IgE (sIgE), and various cytokines and chemokines in those who visited the emergency department for acute asthma exacerbation and classified them according to the season. Findings: HDM-sIgE levels were higher in those presenting with asthma exacerbation in the fall. There was no difference in the levels of cytokines and chemokines between the fall and the other seasons. Conclusion: HDM sensitisation could be a risk factor for asthma exacerbation in the fall.

引用

页码：266 / 272

页数：7

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