Review - Mass spectrometry and protein analysis

被引：1472
作者：
Domon, B [1 ]
Aebersold, R
机构：
[1] ETH, Inst Mol Syst Biol, CH-8093 Zurich, Switzerland
[2] Univ Zurich, Fac Sci, CH-8006 Zurich, Switzerland
[3] Inst Mol Syst Biol, Seattle, WA 98103 USA
来源：
SCIENCE | 2006年 / 312卷 / 5771期
关键词：
D O I：
10.1126/science.1124619
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Mass spectrometry is a central analytical technique for protein research and for the study of biomolecules in general. Driven by the need to identify, characterize, and quantify proteins at ever increasing sensitivity and in ever more complex samples, a wide range of new mass spectrometry based analytical platforms and experimental strategies have emerged. Here we review recent advances in mass spectrometry instrumentation in the context of current and emerging research strategies in protein science.
引用
收藏
页码：212 / 217
页数：6
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