Solitary fibrous tumor in the liver: case report and literature review

被引：22

作者：

Yugawa, Kyohei ^{[1
,2
]}

Yoshizumi, Tomoharu ^{[1
]}

Kano, Yohei ^{[1
]}

Kurihara, Takeshi ^{[1
]}

Yoshiya, Shohei ^{[1
]}

Takeishi, Kazuki ^{[1
]}

Itoh, Shinji ^{[1
]}

Harada, Noboru ^{[1
]}

Ikegami, Toru ^{[1
]}

Soejima, Yuji ^{[1
]}

Kohashi, Kenichi ^{[2
]}

Oda, Yoshinao ^{[2
]}

Mori, Masaki ^{[1
]}

机构：

[1] Kyushu Univ, Dept Surg & Sci, Grad Sch Med Sci, Fukuoka, Fukuoka, Japan

[2] Kyushu Univ, Dept Anat Pathol, Grad Sch Med Sci, Fukuoka, Fukuoka, Japan

来源：

SURGICAL CASE REPORTS | 2019年 / 5卷 / 1期

关键词：

Solitary fibrous tumor; Malignant; Radiology and pathology; NAB2-STAT6 GENE FUSION; VARIANTS; DISTINCT;

D O I：

10.1186/s40792-019-0625-6

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BackgroundSolitary fibrous tumors (SFTs) are uncommon mesenchymal neoplasms that present most commonly at intrathoracic sites. SFTs of the liver are rare, with only a few having been reported in the English-language literature. We report a rare case of a hepatic SFT and literature review.Case presentationA 49-year-old woman underwent surgery for a cranial hemangiopericytoma two decades previously. She currently presented with malaise. Abdominal computed tomography (CT) showed a huge, sharply demarcated mass in the anterior segment of the liver. Tumor marker levels were within the normal range. Following central bisegmentectomy of the liver, histological examination of the specimen revealed that the tumor was composed of spindle and fibroblast-like cells with collagenous stroma. Immunohistochemically, the spindle cells were negative for CD34 but positive for STAT6. The NAB2-STAT6 fusion gene was detected by the reverse transcription polymerase chain reaction. A diagnosis of SFT was thus confirmed histopathologically and genetically.ConclusionsThe SFT of the liver is an uncommon finding. Because there are no specific imaging features, it is difficult to diagnose the hepatic SFT preoperatively. We consider that careful surgical resection and postoperative follow-up are necessary for hepatic SFTs.

引用

页数：6

共 21 条

[1] Solitary Fibrous Tumors/Hemangiopericytomas with Different Variants of the NAB2-STAT6 Gene Fusion Are Characterized by Specific Histomorphology and Distinct Clinicopathological Features [J].