Applications of PET in Diagnosis and Prognosis of Leukemia

被引：20
作者：
Zhao, Zixuan [1 ]
Hu, Yanwen [1 ]
Li, Jihui [1 ]
Zhou, Yeye [1 ]
Zhang, Bin [1 ]
Deng, Shengming [1 ]
机构：
[1] Soochow Univ, Affiliated Hosp 1, Dept Nucl Med, 188 Shizi St, Suzhou 215006, Peoples R China
来源：
TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2020年 / 19卷
关键词：
PET; FDG; leukemia; diagnosis; prognosis; extramedullary; POSITRON-EMISSION-TOMOGRAPHY; VERSUS-HOST-DISEASE; CHRONIC LYMPHOCYTIC-LEUKEMIA; STEM-CELL TRANSPLANTATION; BONE-MARROW-TRANSPLANTATION; ACUTE MYELOID-LEUKEMIA; F-18-FDG PET/CT; FDG-PET/CT; RICHTERS TRANSFORMATION; EXTRAMEDULLARY RELAPSE;
D O I：
10.1177/1533033820956993
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
As a malignant hematopoietic stem cell disease, leukemia remains life-threatening due to its increasing incidence rate and mortality rate. Therefore, its early diagnosis and treatment play a very important role. In the present work, we systematically reviewed the current applications and future directions of positron emission tomography (PET) in patients with leukemia, especially(18)F-FDG PET/CT. As a useful imaging approach, PET significantly contributes to the diagnosis and treatment of different types of leukemia, especially in the evaluation of extramedullary infiltration, monitoring of leukemia relapse, detection of Richter's transformation (RT), and assessment of the inflammatory activity associated with acute graft versus host disease. Future investigations should be focused on the potential of PET/CT in the prediction of clinical outcomes in patients with leukemia and the utility of novel radiotracers.
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页数：12
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