Intravascular pulmonary lymphoma with good response to treatment. A case report

被引:0
作者
Felizardo, M. [1 ,2 ,3 ]
Mendes, A. C. [1 ,2 ,3 ]
Fernandes, A. [1 ,2 ,3 ]
Campos, P. [1 ,4 ,5 ]
Magalhaes, V. [1 ,2 ,3 ]
Correia, I. [1 ,2 ,3 ]
Pignatelli, A. [1 ,4 ,5 ]
Ferreira, C. [1 ,4 ,5 ]
Sotto-Mayor, R. [1 ,4 ,5 ]
de Almeida, A. Bugalho [1 ,4 ,5 ]
机构
[1] Univ Lisbon, Sch Med, Fac Med, P-1699 Lisbon, Portugal
[2] Univ Lisbon, Sch Med, Serv Anat Patol, P-1699 Lisbon, Portugal
[3] Univ Lisbon, Sch Med, Anat Pathol Unit, P-1699 Lisbon, Portugal
[4] Univ Lisbon, Sch Med, Serv Pneumol, P-1699 Lisbon, Portugal
[5] Univ Lisbon, Sch Med, Pulmonol Unit, P-1699 Lisbon, Portugal
关键词
Lymphoma; intravascular; fever; pulmonary;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Intravascular lymphoma is a very rare form of large B cell non-Hodgkin's lymphoma, characterised by the presence of lymphoma cells in the lumina of small vessels only, particulary in the capillaries. We report a 54 year-old female non-smoker, admitted to hospital for further examination of a four month long clinical condition involving high fever, night sweats, unqualified weight loss and progressive dyspnea. Patient's temperature was 38.5 degrees C, pulse 100/min and respiratory 22 cycles/min. Patient's haemoglobin was 9.4g/dL, she had leukocytosis, elevated LDH and arterial blood gas analysis with moderate hypoxaerriia (FiO(2) 1l/m: PaO(2)-63.6 mm Hg). Chest X-ray revealed diffuse interstitial changes. All the possible causes of unknown origin fever were excluded. Diagnosis was made through lung biopsy and treatment with combined chemotherapy and rituximab was prescribed leading to a 48 hours clinical remission. We present this case to show how difficult this diagnosis can be and how a good response to therapy is possible.
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收藏
页码:857 / 868
页数:12
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