Characterisation of the ecotoxicity of hospital effluents: A review

被引:169
作者
Orias, Frederic [1 ]
Perrodin, Yves [1 ]
机构
[1] Univ Lyon, ENTPE, CNRS, UMR LEHNA 5023, F-69518 Vaulx En Velin, France
关键词
Hospital wastewater; Ecotoxicity; Chemical pollutants; Pharmaceuticals; PNEC; WASTE-WATER TREATMENT; ENVIRONMENTAL RISK-ASSESSMENT; TANDEM MASS-SPECTROMETRY; SOLID-PHASE EXTRACTION; PERSONAL CARE PRODUCTS; SURFACE WATERS; HUMAN PHARMACEUTICALS; AQUATIC ORGANISMS; TREATMENT PLANTS; PRIORITY PHARMACEUTICALS;
D O I
10.1016/j.scitotenv.2013.02.064
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The multiple activities that take place in hospitals (surgery, drug treatments, radiology, cleaning of premises and linen, chemical and biological analysis laboratories, etc.), are a major source of pollutant emissions into the environment (disinfectants, detergents, drug residues, etc.). Most of these pollutants can be found in hospital effluents (HWW), then in urban sewer networks and WWTP (weakly adapted for their treatment) and finally in aquatic environments. In view to evaluating the impact of these pollutants on aquatic ecosystems, it is necessary to characterise their ecotoxicity. Several reviews have focused on the quantitative and qualitative characterisation of pollutants present in HWW. However, none have focused specifically on the characterisation of their experimental ecotoxicity. We have evaluated this according to two complementary approaches: (i) a "substance" approach based on the identification of the experimental data in the literature for different substances found in hospital effluents, and on the calculation of their PNEC (Predicted Non Effect Concentration), (ii) a "matrix" approach for which we have synthesised ecotoxicity data obtained from the hospital effluents directly. This work first highlights the diversity of the substances present within hospital effluents, and the very high ecotoxicity of some of them (minimum PNEC observed close to 0,01 pg/L). We also observed that the consumption of drugs in hospitals was a predominant factor chosen by authors to prioritise the compounds to be sought. Other criteria such as biodegradability, excretion rate and the bioaccumulability of pollutants are considered, though more rarely. Studies of the ecotoxicity of the particulate phase of effluents must also be taken into account. It is also necessary to monitor the effluents of each of the specialised departments of the hospital studied. These steps is necessary to define realistic environmental management policies for hospitals (replacement of toxic products by less pollutant ones, etc.). (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:250 / 276
页数:27
相关论文
共 94 条
[11]   Determination of antibiotics in sewage from hospitals, nursery and slaughter house, wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China [J].
Chang, Xiaosong ;
Meyer, Michael T. ;
Liu, Xiaoyun ;
Zhao, Qing ;
Chen, Hao ;
Chen, Ji-an ;
Qiu, Zhiqun ;
Yang, Lan ;
Cao, Jia ;
Shu, Weiqun .
ENVIRONMENTAL POLLUTION, 2010, 158 (05) :1444-1450
[12]   COLLOID-FACILITATED GROUNDWATER CONTAMINANT TRANSPORT [J].
CORAPCIOGLU, MY ;
JIANG, SY .
WATER RESOURCES RESEARCH, 1993, 29 (07) :2215-2226
[13]   Effects of human pharmaceuticals on aquatic life: Next steps [J].
Cunningham, Virginia L. ;
Buzby, Mary ;
Hutchinson, Thomas ;
Mastrocco, Frank ;
Parke, Neil ;
Roden, Nicholas .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2006, 40 (11) :3456-3462
[14]  
DANIEL P, 1981, EUR J CANCER CLIN ON, V17, P1183
[15]   Evaluation of the aquatic toxicity of two veterinary sulfonamides using five test organisms [J].
De Liguoro, Marco ;
Di Leva, Vincenzo ;
Gallina, Guglielmo ;
Faccio, Elisabetta ;
Pinto, Gabriele ;
Pollio, Antonino .
CHEMOSPHERE, 2010, 81 (06) :788-793
[16]   Phototransformation products of tamoxifen by sunlight in water. Toxicity of the drug and its derivatives on aquatic organisms [J].
DellaGreca, Marina ;
Iesce, Maria Rosaria ;
Isidori, Marina ;
Nardelli, Angela ;
Previtera, Lucio ;
Rubino, Maria .
CHEMOSPHERE, 2007, 67 (10) :1933-1939
[17]   Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae [J].
Eguchi, K ;
Nagase, H ;
Ozawa, M ;
Endoh, YS ;
Goto, K ;
Hirata, K ;
Miyamoto, K ;
Yoshimura, H .
CHEMOSPHERE, 2004, 57 (11) :1733-1738
[18]   Ecotoxicological risk assessment of hospital wastewater: a proposed framework for raw effluents discharging into urban sewer network [J].
Emmanuel, E ;
Perrodin, Y ;
Keck, G ;
Blanchard, JM ;
Vermande, P .
JOURNAL OF HAZARDOUS MATERIALS, 2005, 117 (01) :1-11
[19]   Toxicological effects of disinfections using sodium hypochlorite on aquatic organisms and its contribution to AOX formation in hospital wastewater [J].
Emmanuel, E ;
Keck, G ;
Blanchard, JM ;
Vermande, P ;
Perrodin, Y .
ENVIRONMENT INTERNATIONAL, 2004, 30 (07) :891-900
[20]   Recent Advances in Environmental Risk Assessment of Transformation Products [J].
Escher, Beate I. ;
Fenner, Kathrin .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2011, 45 (09) :3835-3847