Salt-free synthesis of tertiary amines by ruthenium-catalyzed amination of alcohols

被引：106
作者：
Tillack, Annegret [1 ]
Hollmann, Dirk [1 ]
Mevius, Kathleen [1 ]
Michalik, Dirk [1 ]
Baehn, Sebastian [1 ]
Beller, Matthias [1 ]
机构：
[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 28期
关键词：
ruthenium; amination; alcohols;
D O I：
10.1002/ejoc.200800671
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The amination of secondary alcohols to give tertiary amines in the presence of different in situ generated ruthenium catalysts has been investigated in detail. By applying a combination of [Ru-3(CO)(12)] and N-phenyl-2-(dicyclohexylphosphanyl)pyrrole as the catalyst, cyclic amines can be alkylated with different alcohols in high yield, whereas aliphatic amines gave transalkylation side products. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).
引用
收藏
页码：4745 / 4750
页数：6
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