Beyond the placental bed: Placental and systemic determinants of the uterine artery Doppler waveform

被引：46
作者：
Everett, T. R. [1 ]
Lees, C. C. [1 ,2 ]
机构：
[1] Cambridge Univ Hosp NHS Trust, Rosie Hosp, Dept Fetal Med, Cambridge CB2 25W, England
[2] Katholieke Univ Leuven, Dept Dev & Regenerat, Louvain, Belgium
来源：
PLACENTA | 2012年 / 33卷 / 11期
关键词：
Uterine artery Doppler; Placenta; Ultrasound; FLOW VELOCITY WAVEFORMS; UTEROPLACENTAL BLOOD-FLOW; INTRAUTERINE GROWTH RESTRICTION; POLYCYSTIC-OVARY-SYNDROME; NORMAL MENSTRUAL-CYCLE; NITRIC-OXIDE DONOR; MATERNAL HEART-RATE; SPIRAL ARTERIES; HYPERTENSIVE DISORDERS; SEVERE PREECLAMPSIA;
D O I：
10.1016/j.placenta.2012.07.011
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The uterine artery Doppler waveform has been extensively investigated, though its widespread clinical use as a predictor of adverse pregnancy outcome remains under debate. The determinants of the waveform have classically been ascribed to transformation of the spiral arteries and the development of a low resistance uteroplacental circulation, failure of which predisposes to pre-eclampsia, fetal growth restriction and other adverse outcomes. It has become increasingly evident that although spiral artery transformation determines in some part the characteristics of the Doppler waveform, factors pertaining to maternal vascular and endothelial function are also important. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：893 / 901
页数：9
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