Preimplantation genetic screening to improve in vitro fertilization pregnancy rates: a prospective randomized controlled trial

被引：48
作者：
Mersereau, Jennifer E. [1 ]
Ergament, Eugene P. [2 ]
Zhang, Xingqi [3 ]
Milad, Magdy P. [3 ]
机构：
[1] Univ Calif San Francisco, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, San Francisco, CA 94143 USA
[2] NW Reprod Genet, Chicago, IL USA
[3] Northwestern Univ, Feinberg Sch Med, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Chicago, IL 60611 USA
来源：
FERTILITY AND STERILITY | 2008年 / 90卷 / 04期
关键词：
D O I：
10.1016/j.fertnstert.2007.08.010
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
This prospective randomized controlled pilot trial was designed to evaluate whether prescreening embryos for aneuploidy can improve clinical outcomes in infertile patients undergoing IVF, without limiting to poor prognosis patients. Although there was no statistically significant improvement in live birth rates or implantation rates in this pilot study, there was a trend toward improved clinical outcomes, indicating that future multicenter randomized trials are needed.
引用
收藏
页码：1287 / 1289
页数：3
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