Preimplantation genetic screening to improve in vitro fertilization pregnancy rates: a prospective randomized controlled trial

被引：48
|
作者：
Mersereau, Jennifer E. [1 ]
Ergament, Eugene P. [2 ]
Zhang, Xingqi [3 ]
Milad, Magdy P. [3 ]
机构：
[1] Univ Calif San Francisco, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, San Francisco, CA 94143 USA
[2] NW Reprod Genet, Chicago, IL USA
[3] Northwestern Univ, Feinberg Sch Med, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Chicago, IL 60611 USA
来源：
FERTILITY AND STERILITY | 2008年 / 90卷 / 04期
关键词：
D O I：
10.1016/j.fertnstert.2007.08.010
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
This prospective randomized controlled pilot trial was designed to evaluate whether prescreening embryos for aneuploidy can improve clinical outcomes in infertile patients undergoing IVF, without limiting to poor prognosis patients. Although there was no statistically significant improvement in live birth rates or implantation rates in this pilot study, there was a trend toward improved clinical outcomes, indicating that future multicenter randomized trials are needed.
引用
收藏
页码：1287 / 1289
页数：3
相关论文
共 50 条
  • [1] A prospective randomized controlled trial of preimplantation genetic screening in the "good prognosis" patient
    Meyer, Liza R.
    Klipstein, Sigal
    Hazlett, William D.
    Nasta, Tricia
    Mangan, Patricia
    Karande, Vishvanath C.
    FERTILITY AND STERILITY, 2009, 91 (05) : 1731 - 1738
  • [2] In vitro fertilization with preimplantation genetic screening
    Mastenbroek, Sebastiaan
    Twisk, Moniek
    van Echten-Arends, Jannie
    Sikkema-Raddatz, Birgit
    Korevaar, Johanna C.
    Verhoeve, Harold R.
    Vogel, Niels E. A.
    Arts, Eus G. J. M.
    de Vries, Jan W. A.
    Bossuyt, Patrick M.
    Buys, Charles H. C. M.
    Heineman, Maas Jan
    Repping, Sjoerd
    van der Veen, Fulco
    NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (01): : 9 - 17
  • [3] Preimplantation genetic screening for aneuploidy of embryos after in vitro fertilization in women aged at least 35 years: a prospective randomized trial
    Debrock, Sophie
    Melotte, Cindy
    Spiessens, Carl
    Peeraer, Karen
    Vanneste, Evelyne
    Meeuwis, Luc
    Meuleman, Christel
    Frijns, Jean-Pierre
    Vermeesch, Joris R.
    D'Hooghe, Thomas M.
    FERTILITY AND STERILITY, 2010, 93 (02) : 364 - 373
  • [4] Randomized controlled trial: effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization
    Moy, Irene
    Milad, Magdy P.
    Barnes, Randall
    Confino, Edmond
    Kazer, Ralph R.
    Zhang, Xingqi
    FERTILITY AND STERILITY, 2011, 95 (02) : 583 - 587
  • [5] Phytoestrogens may improve the pregnancy rate in in vitro fertilization-embryo transfer cycles: a prospective, controlled, randomized trial
    Unfer, V
    Casini, ML
    Gerli, S
    Costabile, L
    Mignosa, M
    Di Renzo, GC
    FERTILITY AND STERILITY, 2004, 82 (06) : 1509 - 1513
  • [6] PREIMPLANTATION GENETIC SCREENING (PGS) IN LOW RESPONDERS SHORTENS TIME TO PREGNANCY: A RANDOMIZED CONTROLLED TRIAL
    Franasiak, J. M.
    Hong, K. H.
    Werner, M. D.
    Juneau, C. R.
    Morin, S. J.
    Neal, S. A.
    Molinaro, T.
    Scott, R. T., Jr.
    FERTILITY AND STERILITY, 2017, 108 (03) : E60 - E61
  • [7] In vitro fertilization with preimplantation genetic screening - Reply
    Mastenbroek, Sebastiaan
    van der Veen, Fulco
    Repping, Sjoerd
    NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (17): : 1770 - 1771
  • [8] Effectiveness of acupuncture on pregnancy success rates for women undergoing in vitro fertilization: A randomized controlled trial
    Guven, Pinar Gursoy
    Cayir, Yasemin
    Borekci, Bunyamin
    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2020, 59 (02): : 282 - 286
  • [9] Blastocyst transfer, decreases multiple pregnancy rates in in vitro fertilization cycles: a randomized controlled trial
    Frattarelli, JL
    Leondires, MP
    McKeeby, JL
    Miller, BT
    Segars, JH
    FERTILITY AND STERILITY, 2003, 79 (01) : 228 - 230
  • [10] Preimplantation genetic screening (PGS) for aneuploidy in embryos after in vitro fertilization (IVF) does not improve reproductive outcome in women over 35: A prospective controlled randomized study.
    Debrock, S.
    Melotte, C.
    Vermeesch, J.
    Spiessens, C.
    Vanneste, E.
    D'Hooghe, T. M.
    FERTILITY AND STERILITY, 2007, 88 : S237 - S237
12345