The comorbidity of epilepsy and depression: diagnosis and treatment

被引：14

作者：

Tao, Kaiyan ^{[1
]}

Wang, Xuefeng ^{[2
,3
]}

机构：

[1] Chongqing Med Univ, Dept Neurol, Chongqing Key Lab Neurol, Affiliated Hosp 1, Chongqing, Peoples R China

[2] Beijing Inst Brain Disorders, Ctr Epilepsy, Chongqing Key Lab Neurol, Beijing, Peoples R China

[3] Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing, Peoples R China

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2016年 / 16卷 / 11期

基金：

中国国家自然科学基金;

关键词：

Epilepsy; depression; comorbidity; diagnosis; treatment; vigabatrin; topiramate; levetiracetam; TEMPORAL-LOBE EPILEPSY; INTERICTAL DYSPHORIC DISORDER; PSYCHIATRIC ADVERSE EVENTS; QUALITY-OF-LIFE; RISK-FACTORS; POSTOPERATIVE DEPRESSION; CLINICAL-PRACTICE; MAJOR DEPRESSION; RETROSPECTIVE ANALYSIS; HIPPOCAMPAL SCLEROSIS;

D O I：

10.1080/14737175.2016.1204233

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: Depression can seriously affect the quality of life of epileptic patients and can even lead to suicide. Understanding the regularity, prevention and treatment of depression in patients with epilepsy (PWE) contributes to the improvement of their quality of life.Areas covered: In this paper, we retrospectively analyzed the relevant literature on the pathogenesis, related factors, clinical characteristics, diagnosis and treatment of depression in PWE. A literature search utilized the PubMed, Embase and Google Scholar databases.Expert commentary: PWE often have depression, which can be the result of seizures, antiepileptic drugs (AEDs) or social-demographic factors. It needs to be better understood, and the diagnosis should be more comprehensive for early treatment.

引用

页码：1321 / 1333

页数：13

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