Intraductal Papillary Mucinous Neoplasm of the Pancreas: Current Perspectives

被引:10
作者
Dumlu, Ersin Gurkan [1 ]
Karakoc, Derya [2 ]
Ozdemir, Arif [2 ]
机构
[1] Ataturk Training & Res Hosp, Dept Gen Surg, TR-06800 Ankara, Turkey
[2] Hacettepe Univ, Fac Med, Dept Gen Surg, TR-06100 Ankara, Turkey
关键词
Intraductal papillary mucinous neoplasm; Pancreas; Treatment options; INTERNATIONAL CONSENSUS GUIDELINES; TERM-FOLLOW-UP; CLINICOPATHOLOGICAL CHARACTERISTICS; CYSTIC NEOPLASMS; DUCT LESIONS; RESECTION; MANAGEMENT; TUMORS; CLASSIFICATION; FEATURES;
D O I
10.9738/INTSURG-D-14-00220.1
中图分类号
R61 [外科手术学];
学科分类号
摘要
In this article, we aimed to review the literature on the clinics and management of intraductal papillary mucinous neoplasm (IPMN). Intraductal papillary mucinous neoplasm of the pancreas is a mucin-producing cystic mass originating from the pancreatic ductal system. Approximately 25% of the pancreatic neoplasms resected surgically and 50% of pancreatic cysts detected incidentally are IPMNs. They can be benign or malignant in character, while malignant transformation of benign forms can be encountered. It is important to determine IPMNs in the early stages, implementation of appropriate treatment approaches, and follow-up to provide better prognosis. We reviewed the studies published in the English medical literature through PubMed and summarized the clinical features and current approaches to the treatment and follow-up of the IPMN. Due to the recent advances and widespread implementation of radiological imaging techniques, the incidental detection rate of IPMNs has increased significantly. The effective treatment of the disease is possible via the detailed diagnosis of the disease, determination of the prognostic factors, and a multidisciplinary approach. Recent literature also emphasized the molecular profile determination approaches for assessment of prognosis of patients with IPMN. Current knowledge on IPMN, a clinically important epidemiologic problem, shows that the treatment should be personalized considering the prognostic features and life expectancy of the patient.
引用
收藏
页码:1060 / 1068
页数:9
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