Aureobasidium pullulans infection in a patient with chronic lymphocytic leukemia

被引：11

作者：

de Oliveira, Leonardo Rodrigues ^{[1
]}

Moraes-Souza, Hello ^{[1
]}

Maltos, Andre Luiz ^{[2
]}

dos Santos, Keila Cristina ^{[3
]}

Molina, Rodrigo Juliano ^{[4
]}

Barata, Cristina Hueb ^{[4
]}

机构：

[1] Univ Fed Triangulo Mineiro, Serv Hematol, Uberaba, MG, Brazil

[2] Univ Fed Triangulo Mineiro, Hosp Clin, Cent Lab, Uberaba, MG, Brazil

[3] Univ Fed Triangulo Mineiro, Hosp Clin, Lab Micol, Uberaba, MG, Brazil

[4] Univ Fed Triangulo Mineiro, Serv Infectol, Uberaba, MG, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2013年 / 46卷 / 05期

关键词：

Aureobasidium pullulans; Subcutaneous mycosis; Phaeohyphomycosis; Chronic lymphocytic leukemia; SUBCUTANEOUS MYCOSIS; FUNGEMIA;

D O I：

10.1590/0037-8682-0117-2013

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Saprophytic fungi are being increasingly recognized as etiologic agents of mycoses in immunosuppressed patients. We report a case of subcutaneous infiltration by Aureobasidium pullulans, likely due to traumatic inoculation, in a neutropenic patient during chemotherapy for chronic lymphocytic leukemia. The patient was treated with amphotericin B deoxycholate but was subsequently switched to itraconazole, which improved the lesion. This case highlights the importance of considering unusual fungal infections in critically ill patients such as those who are immunosuppressed due to chemotherapy. Diagnostic techniques and effective antifungal therapy have improved the prognosis of these cases.

引用

页码：660 / 662

页数：3

共 12 条

[1] Disseminated nosocomial fungal infection by Aureobasidium pullulans var. melanigenum:: a case report [J].

Bolignano, G ;

Criseo, G .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (09) :4483-4485

[2]

de Morais OO, 2011, BRAZ J INFECT DIS, V15, P288, DOI 10.1016/S1413-8670(11)70191-X

[3] Aureobasidium pullulans infection:: Fungemia in an infant and a review of human cases [J].

Hawkes, M ;

Rennie, R ;

Sand, C ;

Vaudry, W .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2005, 51 (03) :209-213

[4] Catheter-related septicemia due to Aureobasidium pullulans [J].

Huang, Yu-Tsung ;

Liao, Chun-Hsing ;

Huang, Yu-Tsung ;

Liaw, Shwu-Jen ;

Yang, Jia-Ling ;

Lai, Dar-Ming ;

Lee, Yung-Chie ;

Hsueh, Po-Ren .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2008, 12 (06) :E137-E139

[5] Peritonitis by Aureobasidium pullulans in continuous ambulatory peritoneal dialysis [J].

IbanezPerez, R ;

Chacon, J ;

Fidalgo, A ;

Martin, J ;

Paraiso, V ;

MunozBellido, JL .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 1997, 12 (07) :1544-1545

[6] Subcutaneous mycosis and fungemia by Aureobasidium pullulans: a rare pathogenic fungus in a post allogeneic BM transplant patient [J].

Joshi, A. ;

Singh, R. ;

Shah, M. S. ;

Umesh, S. ;

Khattry, N. .

BONE MARROW TRANSPLANTATION, 2010, 45 (01) :203-204

[7] Extended fungal skin infection due to Aureobasidium pullulans [J].

Pikazis, D. ;

Xynos, I. D. ;

Xila, V. ;

Velegraki, A. ;

Aroni, K. .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (08) :E892-E894

[8] Chromoblastomycosis produced by Aureobasidium pullulans in an immunosuppressed patient [J].

RedondoBellon, P ;

Idoate, M ;

Rubio, M ;

Herrero, JI .

ARCHIVES OF DERMATOLOGY, 1997, 133 (05) :663-664

[9] Disseminated phaeohyphomycosis: Review of an emerging mycosis [J].

Revankar, SG ;

Patterson, JE ;

Sutton, DA ;

Pullen, R ;

Rinaldi, MG .

CLINICAL INFECTIOUS DISEASES, 2002, 34 (04) :467-476

[10] OPPORTUNISTIC INFECTION OF THE SPLEEN CAUSED BY AUREOBASIDIUM-PULLULANS [J].

SALKIN, IF ;

MARTINEZ, JA ;

KEMNA, ME .

JOURNAL OF CLINICAL MICROBIOLOGY, 1986, 23 (05) :828-831

← 1 2 →