Managing adult Fontan patients: where do we stand?

被引：31

作者：

Clift, Paul ^{[1
]}

Celermajer, David ^{[2
]}

机构：

[1] Univ Hosp Birmingham, Dept Cardiol, Birmingham, W Midlands, England

[2] Royal Prince Alfred Hosp, Dept Cardiol, Sydney, NSW, Australia

来源：

EUROPEAN RESPIRATORY REVIEW | 2016年 / 25卷 / 142期

关键词：

PROTEIN-LOSING ENTEROPATHY; TOTAL CAVOPULMONARY CONNECTION; QUALITY-OF-LIFE; CONGENITAL HEART-DISEASE; INDUCED PULMONARY-HYPERTENSION; HIGH-DOSE SPIRONOLACTONE; TERM FOLLOW-UP; SINGLE VENTRICLE; EXERCISE CAPACITY; EXTRACARDIAC CONDUIT;

D O I：

10.1183/16000617.0091-2016

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The Fontan operation is performed as a palliative procedure to improve survival in infants born with a functionally univentricular circulation. The success of the operation is demonstrated by a growing adult Fontan population that exists with this unique physiology. Late follow-up has demonstrated expected and unexpected sequelae, and has shown multisystem effects of this circulation. This review discusses the challenges of managing the late complications in terms of understanding this unique physiology and the innovative therapeutic interventions that are being investigated. The challenge remains to maintain quality of life for adult survivors, as well as extending life expectancy.

引用

页码：438 / 450

页数：13

共 151 条

[1] The adult with a Fontan operation [J].

Aboulhosn J. ;

Child J.S. .

Current Cardiology Reports, 2007, 9 (4) :331-335

[2] Postcardiotomy ECMO Support after High-risk Operations in Adult Congenital Heart Disease [J].

Acheampong, Benjamin ;

Johnson, Jonathan N. ;

Stulak, John M. ;

Dearani, Joseph A. ;

Kushwaha, Sudhir S. ;

Daly, Richard C. ;

Haile, Dawit T. ;

Schears, Gregory J. .

CONGENITAL HEART DISEASE, 2016, 11 (06) :751-755

[3]

Akbari Asbagh Parvin, 2014, J Tehran Heart Cent, V9, P59

[4] Thoracic Duct Decompression for Protein-Losing Enteropathy in Failing Fontan Circulation [J].

Antonio, Marta ;

Gordo, Andreia ;

Pereira, Conceicao ;

Pinto, Fatima ;

Fragata, Isabel ;

Fragata, Jose .

ANNALS OF THORACIC SURGERY, 2016, 101 (06) :2370-2373

[5] Diagnosis of occult diastolic dysfunction late after the Fontan procedure using a rapid volume expansion technique [J].

Averin, Konstantin ;

Hirsch, Russel ;

Seckeler, Michael D. ;

Whiteside, Wendy ;

Beekman, Robert H., III ;

Goldstein, Bryan H. .

HEART, 2016, 102 (14) :1109-1114

[6] Deficits in bone density and structure in children and young adults following Fontan palliation [J].

Avitabile, Catherine M. ;

Goldberg, David J. ;

Zemel, Babette S. ;

Brodsky, Jill L. ;

Dodds, Kathryn ;

Hayden-Rush, Christina ;

Whitehead, Kevin K. ;

Goldmuntz, Elizabeth ;

Rychik, Jack ;

Leonard, Mary B. .

BONE, 2015, 77 :12-16

[7] Sinus node dysfunction after Fontan modifications - influence of surgical method [J].

Bae, EJ ;

Lee, JY ;

Noh, CI ;

Kim, WH ;

Kim, YJ .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2003, 88 (2-3) :285-291

[8]

BALAJI S, 1991, CIRCULATION, V84, P162

[9] ARRHYTHMIAS AND ELECTROCARDIOGRAPHIC CHANGES AFTER THE HEMI-FONTAN PROCEDURE [J].

BALAJI, S ;

CASE, CL ;

SADE, RM ;

GILLETTE, PC .

AMERICAN JOURNAL OF CARDIOLOGY, 1994, 73 (11) :828-829

[10] Intracardiac thrombus formation after the Fontan operation [J].

Balling, G ;

Vogt, M ;

Kaemmerer, H ;

Eicken, A ;

Meisner, H ;

Hess, J .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2000, 119 (04) :745-751

← 1 2 3 4 5 6 7 8 9 10 →