Laser in situ keratomileusis for high hyperopia (>5.0 diopters) using optimized aspheric profiles: Efficacy and safety

PURPOSE: To evaluate the clinical outcomes of laser in situ keratomileusis (LASIK) for high hyperopia using an excimer laser and optimized aspheric profiles. SETTING: Vissum Corporation and Miguel Hernandez University, Alicante, Spain, and Research Institute of Ophthalmology, Giza, Egypt. DESIGN: Case series. METHODS: Eyes of patients with high hyperopia or hyperopic astigmatism (spherical equivalent [SE] >= 5.64 diopters [D]) had uneventful LASIK with an aspheric optimized ablation profile centered on the corneal vertex using an Amaris 500 kHz excimer laser and a femtosecond platform for flap creation with a temporal hinge. RESULTS: There was a significant improvement in uncorrected distance visual acuity 3 months postoperatively (P<.01), with no significant changes afterward (P=.72). At 6 months, the corrected distance visual acuity (CDVA) remained unchanged or improved in 90.48% of eyes; 2 eyes (9.52%) lost 2 lines of logMAR CDVA. The postoperative SE was within +/- 0.50 D of emmetropia in 70.37% of eyes. The LASIK enhancement rate at the end of the follow-up was 29.4%. Significant induction of corneal primary spherical aberration and coma was found with 6.0 mm pupils (P<.01). The safety index was 0.94 and the efficacy index, 0.85. CONCLUSION: Laser in situ keratomileusis for high hyperopia using optimized aspheric profiles requires further improvement in terms of safety but was still an effective and a predictable procedure.