Two cases of CD30+, anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma with oral manifestations

被引：5

作者：

Grandhi, Anupama ^{[1
]}

Boros, Audrey L. ^{[1
]}

Berardo, Nicholas ^{[2
]}

Reich, Renee F. ^{[1
,3
]}

Freedman, Paul D. ^{[1
,3
]}

机构：

[1] New York Hosp Queens, Sect Oral & Maxillofacial Pathol, New York, NY USA

[2] Hackensack Univ, Med Ctr, Hackensack, NJ USA

[3] New York Hosp Queens, Oral & Maxillofacial Pathol Residency Program, New York, NY USA

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY | 2013年 / 115卷 / 02期

关键词：

EXPRESSION; MUCOSA; CAVITY;

D O I：

10.1016/j.oooo.2012.04.010

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Anaplastic large cell lymphoma (ALCL), a subgroup of T-cell non-Hodgkin's lymphoma, is an uncommon tumor exhibiting CD30 positivity and a characteristic immunophenotypic profile. Histologically, ALCL is characterized by the proliferation of large, anaplastic lymphoid cells with eccentric horseshoe- or kidney-shaped nuclei and one or more prominent nucleoli. Rare cases have been cited in the literature of ALCL presenting primarily in the oral cavity. The purpose of this article was to present 2 instructive cases of CD30+, anaplastic lymphoma kinase-negative ALCL with oral and systemic involvement. (Oral Surg Oral Med Oral Pathol Oral Radiol 2013;115:e41-e47)

引用

页码：E41 / E47

页数：7

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