Dumping Symptoms and Incidence of Hypoglycaemia After Provocation Test at 6 and 12 Months After Laparoscopic Sleeve Gastrectomy

被引:78
作者
Papamargaritis, Dimitris [1 ]
Koukoulis, George [1 ]
Sioka, Eleni [2 ]
Zachari, Eleni [2 ]
Bargiota, Alexandra [1 ]
Zacharoulis, Dimitris [2 ]
Tzovaras, George [2 ]
机构
[1] Univ Hosp Larissa, Dept Endocrinol, Larisa, Greece
[2] Univ Hosp Larissa, Dept Surg, Larisa, Greece
关键词
Laparoscopic sleeve gastrectomy; Bariatric surgery; Dumping syndrome; Gastric emptying; Hypoglycaemia; Late dumping; Y GASTRIC BYPASS; BETA-CELL FUNCTION; WEIGHT-LOSS; BARIATRIC SURGERY; PEPTIDE-YY; GASTROPLASTY; IMPROVEMENT; APPETITE; TRIAL;
D O I
10.1007/s11695-012-0711-3
中图分类号
R61 [外科手术学];
学科分类号
摘要
A previous study has demonstrated that symptoms suggestive of dumping syndrome appear after a provocation test early after laparoscopic sleeve gastrectomy (LSG) in 45 % of patients, and these are mainly related to early dumping. The aim of this study is to evaluate the evolution of dumping symptoms during the first postoperative year. Twenty-five non-diabetic morbidly obese patients (6 male, 19 female) were evaluated with an oral glucose tolerance test (OGTT) preoperatively, at 6 weeks and at 6 months postoperatively. In addition, 12 of them repeated the OGTT at 12 months after LSG. Sigstad score was used to separate dumpers from non-dumpers and Arts' questionnaire to differentiate between early and late dumping. Insulin and glucose levels were also measured. Sigstad score remained significantly elevated at 6 and 12 months postoperatively compared to preoperative values. Symptoms suggestive of dumping syndrome were recorded in 40 % of patients at 6 months and in 33 % at 12 months postoperatively. Arts' questionnaire demonstrated that early dumping score remained higher compared to baseline at 6 and 12 months postoperatively. Late dumping scores increased gradually during the time and that difference was statistically significant at 12 months after LSG. Hypoglycaemia occurred at 33 % of patients both at 6 and 12 months postoperatively. Symptoms suggestive of dumping syndrome after provocation still exist at 6 and 12 months in a significant proportion of patients after LSG and include both early and late dumping. These findings are consistent with the high incidence of hypoglycaemia after OGTT at 6 and 12 months after LSG.
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收藏
页码:1600 / 1606
页数:7
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