Dummy molecularly imprinted polymer (DMIP) as a sorbent for bisphenol S and bisphenol F extraction from food samples

Dummy molecularly imprinted polymer (DMIP) was prepared towards bisphenol S and bisphenol F employing bisphenol A as a dummy template. Liquid chromatography with UV and fluorescence detection (LC-UV/FLD) was used for the separation and quantification of these analytes. The maximum adsorption capacity of DMIP was 20.9 mg g(-1) and 18.6 mg g(-1) for BPS and BPF, respectively. By applying solid phase extraction with DMIP prior to LC-UV/FLD, the limits of detections achieved in food samples can be lowered to 0.5 ng g(-1) for BPF and 5 ng g(-1) for BPS. Only 5 mg of DMIP sorbent was sufficient to achieve good recoveries (71-113%) and precision (RSD 0.1-3.2%, n = 3) for analyzed liquid food samples spiked at two concentration levels 0.25 mg(-1) and 0.40 mg L-1. For preconcentrated pineapple extract spiked with 0.5 mg.L-1 of both analytes, also very good recovery was obtained (89% for BPS and 99% for BPF), significantly higher than for conventional SPE cartridges such as Oasis HLB and Affinimip (R). The analytical characterization of the proposed method makes it suitable for monitoring programs, intended for the assessment of human exposure to bisphenol S in food samples, without using much expensive mass spectrometry detection.