Chemical Composition, Antioxidant, Antimicrobial and Antispasmodic Activities of the Essential Oil of Juniperus excelsa subsp excelsa

被引：17

作者：

Atas, Ahmet Duran ^{[1
]}

Goze, Ismihan ^{[2
]}

Alim, Ahmet ^{[3
]}

Cetinus, Senay Akkus ^{[4
]}

Durmus, Nedim ^{[5
]}

Vural, Nilufer ^{[6
]}

Cakmak, Osman ^{[7
]}

机构：

[1] Cumhuriyet Univ, Fac Vet Med, Dept Parasitol, Sivas, Turkey

[2] Cumhuriyet Univ, Vocat Sch Hlth Serv, Sivas, Turkey

[3] Cumhuriyet Univ, Fac Vet Med, Dept Microbiol, Sivas, Turkey

[4] Cumhuriyet Univ, Fac Sci & Literature, Dept Chem, Sivas, Turkey

[5] Cumhuriyet Univ, Sch Med, Dept Pharmacol, Sivas, Turkey

[6] Ankara Univ, Inst Biotechnol, TR-06100 Ankara, Turkey

[7] Gaziosmanpasa Univ, Fac Art & Sci, Dept Chem, Tokat, Turkey

来源：

JOURNAL OF ESSENTIAL OIL BEARING PLANTS | 2012年 / 15卷 / 03期

关键词：

Juniperus excelsa; essential oil; antioxidant; antimicrobial; antispasmodic; MEDICINAL-PLANTS; IN-VITRO; BERRIES; LEAVES; DITERPENES;

D O I：

10.1080/0972060X.2012.10644075

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In this study, chemical composition, antioxidant, antimicrobial and antiospasmodic activities of the essential oil of the berries Juniperus excelsa Bieb. subsp. excelsa were evaluated in vitro. GC and GS-MS analysis of the oil resulted in the identification of 25 compounds, representing 97.2 % of the oil; alpha-pinene (46.1 %) was the main component. Essential oil showed remarkable antimicrobial activity against the test microorganisms. The sample was also subjected to a screening for its possible antioxidant activity by using 2,2-diphenyl-1- picrylhydrazyl (DPPH) and beta-carotene-linoleic acid assays. It was exhibited moderate antioxidant activity in beta-carotene-linoleic acid test system. In rat ileum, J. excelsa essential oil effect was directly investigated on spontaneous contractions. It has been found that amplitude and frequency did not change significantly at all dose concentrations. Amplitude has been inhibited % 25 and frequency has been inhibited % 20 at 1 mg/mL.

引用

页码：476 / 483

页数：8

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