Composite bioceramics/polymer electrospun scaffolds for regenerative medicine

被引：1

作者：

Miramond, T. ^{[1
,2
]}

Borget, P. ^{[2
]}

Colombeix, C. ^{[1
]}

Baroth, S. ^{[2
]}

Daculsi, G. ^{[1
]}

机构：

[1] Univ Nantes, INSERM, Fac Dent, Pl A Ricordeau, F-44042 Nantes, France

[2] Bionnatlante SA, F-44360 Vigneux, France

来源：

BIOCERAMICS 24 | 2013年 / 529-530卷

关键词：

Fibers; biphasic calcium phosphate; composite; scaffold; cell adhesion; RESORBABLE OSTEO SYNTHESIS; SURGICAL TECHNOLOGIES; BONE SUBSTITUTE; FIBER DIAMETER; NANOFIBERS; DIFFERENTIATION; MINERALIZATION; PROLIFERATION; BIOMATERIALS;

D O I：

10.4028/www.scientific.net/KEM.529-530.441

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The main goal of this study was to succeed in the relevant association of well-known osteoconductive biphasic calcium phosphate (BCP) made of Hydroxyapatite (20% HA) and beta-Tricalcium Phosphate (80% beta-TCP) crystallographic phases and resorbable poly(L-lactide-co-D,L-lactide)(PLDLLA) 3D matrices synthesized by electrospinning. Two types of mineral particles were obtained, BCP new hollow granules, and classical BCP particles. It appeared that hollow shells/PLDLLA composite 3D matrices allowed higher cell adhesion in vitro, thanks to internal concavities and are promising scaffolds in terms of cell carrying.

引用

页码：441 / +

页数：3

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