Synthesis of 6-acyl phenanthridines by oxidative radical decarboxylation-cyclization of α-oxocarboxylates and isocyanides

被引：151

作者：

Liu, Jie ^{[1
]}

Fan, Chao ^{[1
]}

Yin, Hongyu ^{[1
]}

Qin, Chu ^{[1
]}

Zhang, Guoting ^{[1
]}

Zhang, Xu ^{[1
]}

Yi, Hong ^{[1
]}

Lei, Aiwen ^{[1
,2
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

[2] Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 17期

基金：

高等学校博士学科点专项科研基金;

关键词：

CASCADE REACTIONS; 2-ISOCYANOBIPHENYLS; ISONITRILES; TRIFLUOROMETHYLATION; ANNULATIONS; DERIVATIVES; PYRIDINES; ACIDS;

D O I：

10.1039/c3cc49026b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A silver catalysed synthesis of 6-acyl phenanthridines by oxidative radical decarboxylation-cyclization of alpha-oxocarboxylates and isocyanides was developed. This reaction provided a novel method to realize C1 insertion via a radical process and various functional groups were well-tolerated.

引用

页码：2145 / 2147

页数：3

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