Cardiovascular risk in patients with inflammatory bowel diseases: a review

被引：6

作者：

Manea, Maria ^{[1
]}

Marcu, Dragos ^{[1
,3
]}

Motofei, Ion ^{[2
,3
]}

Socea, Bogdan ^{[2
,3
]}

Stoian, Anca Pantea ^{[3
]}

Bratu, Ovidiu Gabriel ^{[1
,3
]}

Gaman, Mihnea-Alexandru ^{[3
]}

Gaman, Amelia Maria ^{[4
]}

Stanescu, Ana Maria Alexandra ^{[3
]}

Nicorici, Lucia Mazur ^{[5
]}

Diaconu, Camelia Cristina ^{[3
,6
]}

机构：

[1] Emergency Univ Cent Mil Hosp, Bucharest, Romania

[2] St Pantelimon Clin Emergency Hosp, Bucharest, Romania

[3] Carol Davila Univ Med & Pharm, Bucharest, Romania

[4] Univ Med & Pharm Craiova, Filantropia City Hosp, Craiova, Romania

[5] State Univ Med & Pharm Nicolae Testemitanu, Kishinev, Moldova

[6] Clin Emergency Hosp Bucharest, Bucharest, Romania

来源：

ROMANIAN BIOTECHNOLOGICAL LETTERS | 2019年 / 24卷 / 02期

关键词：

Inflammatory bowel diseases; cardiovascular events; thromboembolic events; atherosclerosis; HIGH-DENSITY-LIPOPROTEIN; ENDOTHELIAL DYSFUNCTION; HEART-DISEASE; POPULATION; EPIDEMIOLOGY; EVENTS; ATHEROSCLEROSIS; HOMOCYSTEINE; PREVALENCE; PREDICTORS;

D O I：

10.25083/rbl/24.2/366.373

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Patients with inflammatory bowel diseases (IBD) have an increased risk of cardiovascular events (myocardial infarction, cerebrovascular events and death of cardiovascular causes), because of some common pathophysiological mechanisms. Patients with IBD have high levels of cytokines, C-reactive protein and homocysteine, leading to endothelial dysfunction and atherosclerosis. Also, the increased levels of coagulation factors in patients with IBD lead to an increased risk for thromboembolic events. There are numerous studies that sustain the link between IBD and cardiovascular complications.

引用

页码：366 / 373

页数：8

共 64 条

[31] Activations of coagulation and fibrinolysis secondary to bowel inflammation in patients with ulcerative colitis [J].