Copper-catalyzed benzylic oxidation of C(sp3)-H bonds

被引：22
|
作者：
Zhang, Bo
Zhu, Shou-Fei [1 ]
Zhou, Qi-Lin
机构：
[1] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China
来源：
TETRAHEDRON | 2013年 / 69卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Copper catalyst; Quinoline-imine ligand; Benzylic oxidation; C(sp(3))-H bond functionalization; C-H BONDS; ENANTIOSELECTIVE ALLYLIC OXIDATION; 2-ARYLACETIC ACID-DERIVATIVES; ALPHA-HYDROXYLATION; COMPLEX; FUNCTIONALIZATION; ACTIVATION; EFFICIENT;
D O I：
10.1016/j.tet.2012.12.046
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A selective oxidation of benzylic C(sp(3))-H bonds to C(sp(3))-O bonds catalyzed by copper complexes of quinoline-imine ligands was developed with peresters as oxidants under mild reaction conditions, which converted benzylic methylenes directly into benzylic alcohols and esters by means of direct C-H bond functionalization. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2033 / 2037
页数：5
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