Contact drying: A review of experimental and mechanistic modeling approaches

被引:36
作者
Sahni, Ekneet Kaur [1 ]
Chaudhuri, Bodhisattwa [1 ,2 ]
机构
[1] Univ Connecticut, Dept Pharmaceut Sci, Storrs, CT 06269 USA
[2] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA
关键词
Contact drying; PAT approaches; Mechanistic modeling; NEAR-INFRARED SPECTROSCOPY; PARTICLE DYNAMICS SIMULATION; CAPILLARY-POROUS MEDIA; FLUIDIZED-BED; HEAT-TRANSFER; QUANTITATIVE-ANALYSIS; TRANSPORT PARAMETERS; CHEMICAL-INDUSTRY; MOISTURE-CONTENT; DRUG SUBSTANCES;
D O I
10.1016/j.ijpharm.2012.06.010
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Drying is one of the most complex unit operations with simultaneous heat and mass transfer. The contact drying process is also not well understood as several physical phenomena occur concurrently. This paper reviews current experimental and modeling approaches employed towards a better understanding of the contact drying operation. Additionally, an overview of some fundamental aspects relating to contact drying is provided. A brief discussion of some model extensions such as incorporation of noncontact forces, interstitial fluids and attrition rate is also presented. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:334 / 348
页数:15
相关论文
共 122 条
[1]   Time-resolved NIR spectroscopy for quantitative analysis of intact pharmaceutical tablets [J].
Abrahamsson, C ;
Johansson, J ;
Andersson-Engels, S ;
Svanberg, S ;
Folestad, S .
ANALYTICAL CHEMISTRY, 2005, 77 (04) :1055-1059
[2]  
Adams M.J., 1987, TRIBOLOGY PARTICULAT, P154
[3]  
[Anonymous], 2008, Practical guide to interpretive near-infrared spectroscopy
[4]  
[Anonymous], 2009, PAK J NUTR, DOI DOI 10.3923/PJN.2009.955.957
[5]  
[Anonymous], 2005, Raman spectroscopy for chemical analysis M
[6]   Identification of the limiting mechanism in contact drying of agitated sewage sludge [J].
Arlabosse, P. ;
Chitu, T. .
DRYING TECHNOLOGY, 2007, 25 (4-6) :557-567
[7]  
Baillon B, 1996, THESIS U PAU PAYS AD
[8]  
Bakeev KA, 2004, SPECTROSCOPY-US, V19, P39
[9]  
Beer T.D., 2011, INT J PHARMACEUT, V417, P32
[10]   Effects of particle size and cohesive properties on mixing studied by non-contact NIR [J].
Bellamy, Luke J. ;
Nordon, Alison ;
Littlejohn, David .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 361 (1-2) :87-91