Options for diagnosis and treatment of urachal carcinoma

被引:27
作者
Zhang, Jianwen [1 ]
Wu, Jingbo [1 ]
机构
[1] Luzhou Med Coll, Affiliated Hosp, Dept Oncol, Luzhou 646000, Sichuan Provinc, Peoples R China
关键词
chemotherapy; diagnosis; prognosis; treatment; urachal carcinoma; TRANSITIONAL-CELL-CARCINOMA; UROTHELIAL TRACT; ADENOCARCINOMA; IFOSFAMIDE; CISPLATIN; CANCER; CHEMOTHERAPY; PACLITAXEL; SURVIVAL; FEATURES;
D O I
10.1111/j.1743-7563.2012.01592.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Urachal carcinoma (UrC) is a rare but highly malignant epithelial cancer and commonly found in the urachal remnant which connects the dome of the bladder to the umbilicus via the ligamentum commune. Because of the specificity of the tumor location and its rarity, the diagnosis of UrC is often difficult. Although surgery is the treatment of choice for UrC, it still has a high incidence of local recurrence and distant metastasis and there are few modestly standard chemotherapy regimens for these patients (response rate 3040%). Thus, the treatment of local recurrence and distant metastasis of UrC following surgery has been a challenge. We review the clinical diagnosis and therapy of UrC and factors related to its prognosis.
引用
收藏
页码:117 / 122
页数:6
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