Ruthenium-catalyzed benzimidazoisoquinoline synthesis via oxidative coupling of 2-arylbenzimidazoles with alkynes

被引：43

作者：

Kavitha, Nerella ^{[1
]}

Sukumar, Genji ^{[1
]}

Kumar, Vemula Praveen ^{[1
]}

Mainkar, Prathama S. ^{[1
]}

Chandrasekhar, Srivari ^{[1
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Div Nat Prod Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 32期

关键词：

Oxidative coupling; Benzimidazoisoquinoline; C-H activation; PEG-400; POLY(ETHYLENE GLYCOL); C-H; HECK REACTION; SYSTEM; PEG;

D O I：

10.1016/j.tetlet.2013.05.106

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of a fused bis-heterocyclic framework, benzimidazoisoquinoline, has been achieved using Ru-catalyzed reaction of alkynes with 2-aryl benzimidazoles in the presence of Cu salts. The method provides an easy access for the generation of a library of benzimidazoisoquinoline derivatives. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：4198 / 4201

页数：4

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