Radiotherapy and Bevacizumab for Intramedullary and Leptomenigeal Metastatic Glioblastoma: A Case Report and Review of the Literature

被引：11

作者：

Fiorentino, Alba ^{[1
]}

Caivano, Rocchina ^{[1
]}

Chiumento, Costanza ^{[1
]}

Cozzolino, Mariella ^{[1
]}

Fusco, Vincenzo ^{[1
]}

机构：

[1] IRCCS CROB, Dept Radiotherapy Oncol, I-85028 Rionero In Vulture, PZ, Italy

来源：

INTERNATIONAL JOURNAL OF NEUROSCIENCE | 2012年 / 122卷 / 11期

关键词：

bevacizumab; glioblastoma; metastases; radiotherapy; SYMPTOMATIC LEPTOMENINGEAL; CEREBRAL GLIOBLASTOMA; MULTIFORME; DISSEMINATION; TUMORS; GLIOMAS;

D O I：

10.3109/00207454.2012.704456

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Glioblastoma (GBM) developed metastases rarely and the prognosis, in these cases, was very poor. We reported a 30-year patient who, developing intramedullary and leptomeningeal metastases from GBM, underwent palliative spinal radiotherapy (RT) and Bevacizumab.

引用

页码：691 / 694

页数：4

共 23 条

[1] Spinal leptomeningeal metastasis from cerebral glioblastoma multiforme presenting with radicular pain - Case report and literature review [J].

Alatakis, S ;

Malham, GM ;

Thien, C .

SURGICAL NEUROLOGY, 2001, 56 (01) :33-37

[2] LEPTOMENINGEAL DISSEMINATION OF MALIGNANT GLIOMAS - INCIDENCE, DIAGNOSIS AND OUTCOME [J].

ARITA, N ;

TANEDA, M ;

HAYAKAWA, T .

ACTA NEUROCHIRURGICA, 1994, 126 (2-4) :84-92

[3] Spinal drop metastases in recurrent glioblastoma multiforme [J].

Buhl, R ;

Barth, H ;

Hugo, HH ;

Hutzelmann, A ;

Mehdorn, HM .

ACTA NEUROCHIRURGICA, 1998, 140 (10) :1001-1005

[4] Combined-modality treatment of leptomeningeal gliomatosis [J].

Chamberlain, MC .

NEUROSURGERY, 2003, 52 (02) :324-329

[5] Spinal leptomeningeal metastases of giant cell glioblastoma associated with subarachnoid haemorrhage: case report [J].

Chang, CC ;

Kuwana, N ;

Ito, S ;

Koike, Y ;

Kitamura, H .

JOURNAL OF CLINICAL NEUROSCIENCE, 2001, 8 (01) :56-59

[6] SYMPTOMATIC LEPTOMENINGEAL METASTASES PRECEDING OTHER MANIFESTATIONS OF OCCULT PRIMARY BRAIN-TUMORS [J].

CORBETT, JJ ;

NEWMAN, NM .

SURGICAL NEUROLOGY, 1981, 15 (05) :362-367

[7]

ERLICH SS, 1978, CANCER-AM CANCER SOC, V42, P2854, DOI 10.1002/1097-0142(197812)42:6<2854::AID-CNCR2820420647>3.0.CO

[8]

2-4

[9]

Fakhrai Negar, 2004, Strahlenther Onkol, V180, P455

[10] Case reports of symptomatic metastases in four patients with primary intracranial gliomas [J].

Hübner, F ;

Braun, V ;

Richter, HP .

ACTA NEUROCHIRURGICA, 2001, 143 (01) :25-29

← 1 2 3 →