Recent advances in understanding and diagnosing hepatitis B virus infection

被引：4
作者：
Fourati, Slim [1 ,2 ]
Pawlotsky, Jean-Michel [1 ,2 ]
机构：
[1] Univ Paris Est, Hop Henri Mondor, Ctr Natl Reference Hepatites Virales B C & Delta, Serv Virol, 51 Ave Mal de Lattre de Tassigny, F-94010 Creteil, France
[2] INSERM, U955, 51 Ave Mal de Lattre de Tassigny, F-94010 Creteil, France
来源：
VIROLOGIE | 2019年 / 23卷 / 01期
关键词：
hepatitis B; HBV RNA; HBcrAg; HBsAg quantification; CORE-RELATED ANTIGEN; CLOSED CIRCULAR DNA; NUCLEOS(T)IDE ANALOG THERAPY; SERUM HBV PGRNA; SURFACE-ANTIGEN; NATURAL-HISTORY; HEPATOCELLULAR-CARCINOMA; HBSAG QUANTIFICATION; ANTIVIRAL TREATMENT; VIRAL-HEPATITIS;
D O I：
10.1684/vir.2019.0760
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
HepatitisBvirus (HBV) infects approximately 257 million individuals worldwide. Recent advances in the virology and diagnosis of HBV infection are summarized in this review article. A novel classification of the different phases of chronic HBV infection, proposed by the European Association for the Study of the Liver (EASL), is presented. New diagnostic and monitoring tools are now available, including rapid diagnostic tests for hepatitisBsurface antigen (HBsAg) detection, HBsAg quantification assays, an HBV core-related antigen (HBcrAg) quantification test, and HBV RNA quantification testing. Their clinical utility under study is discussed in this review.
引用
收藏
页码：23 / 34
页数：12
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