THE HISTORICAL USE OF RADIOTHERAPY IN THE TREATMENT OF SINUS INFECTIONS

被引：20

作者：

Calabrese, Edward J. ^{[1
]}

Dhawan, Gaurav ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Publ Hlth Environm Hlth Sci, Amherst, MA 01003 USA

来源：

DOSE-RESPONSE | 2013年 / 11卷 / 04期

关键词：

sinusitis; radiotherapy; dose response; x-rays; history of medicine; inflammation; DOSE RADIATION-THERAPY; ROENTGEN THERAPY; PARANASAL SINUSES; LD-RT;

D O I：

10.2203/dose-response.13-004.Calabrese

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The aim of this paper is to assess the historical role of radiotherapy in the treatment of sinus infections. This assessment involved a literature-based review of how radiotherapy was used to treat sinus infections in the first half of the 20th century. Low doses of x-rays were used with considerable success to treat nearly 3,000 patients of sinus infection in a span of 12 years with these cases being reported in leading medical journals as case studies. The mechanism of x-ray induced reduction of inflammation and increased tissue repair is uncertain but appears to be related to the development of a multifactorial and integrative anti-inflammatory phenotype.

引用

页码：469 / 479

页数：11

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