Reductive coupling of aliphatic cyclic imides with benzophenones by low-valent titanium

被引：7

作者：

Kise, Naoki ^{[1
]}

Kinameri, Syn ^{[1
]}

Sakurai, Toshihiko ^{[1
]}

机构：

[1] Tottori Univ, Dept Chem & Biotechnol, Grad Sch Engn, Minami Ku, Tottori 6808552, Japan

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 50期

关键词：

Reductive coupling; Low-valent titanium; McMurry coupling; Aliphatic cyclic imides; Benzophenones; ESTROGEN-RECEPTOR MODULATORS; KETONES; LACTAMS;

D O I：

10.1016/j.tetlet.2013.10.053

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reductive coupling of aliphatic cyclic imides with benzophenones by Zn-TiCl4 in THF gave two- and four-electron reduced products selectively by controlling the reaction conditions. Although cyclic and acyclic products were formed as mixtures in most cases, cyclic dehydrated products could be selectively obtained by heating the product mixtures in the presence of cat. p-TsOH. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：6944 / 6948

页数：5

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