Resins with Identical Specifications Are Not Identical. Identifying a Useful Solid-Phase Resin

被引:20
作者
Bouillon, Isabelle [1 ]
Soural, Miroslav [1 ]
Miller, Marvin J. [1 ]
Krchnak, Viktor [1 ]
机构
[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
来源
JOURNAL OF COMBINATORIAL CHEMISTRY | 2009年 / 11卷 / 02期
关键词
PEPTIDE-SYNTHESIS; HETEROCYCLIC-COMPOUNDS; TRACELESS SYNTHESIS; ORGANIC-SYNTHESIS; CHEMISTRY; SUPPORTS;
D O I
10.1021/cc800143e
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The quality of the most commonly used support for solid-phase syntheses, polystyrene resin cross-linked with 1% of divinylbenzene, differs considerably even among different lots of resin from the same source. Determination of the swelling capacity of resins before carrying out solid-phase syntheses represents a very simple means of nondestructive presynthetic resin characterization.
引用
收藏
页码:213 / 215
页数:3
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