Prevalence of refractive errors in Mobius sequence

Purpose: To assess the prevalence of refractive errors in Mobius sequence. Methods: This study was carried out during the Annual Meeting of the Brazilian Mobius Society in November 2008. Forty-four patients diagnosed with the Mobius sequence were submitted to a comprehensive assessment, on the following specialties: ophthalmology, neurology, genetics, psychiatry, psychology and dentistry. Forty-three patients were cooperative and able to undertake the ophthalmological examination. Twenty-two (51.2 %) were male and 21 (48.8%) were female. The average age was 8.3 years (from 2 to 17 years). The visual acuity was evaluated using a retro-illuminated logMAR chart in cooperative patients. All children were submitted to exams on ocular motility, cyclopegic refraction, and fundus examination. Results: From the total of 85 eyes, using the spherical equivalent, the major of the eyes (57.6%) were emmetropics (>-0.50 D and <+ 2.00 D). The prevalence of astigmatism greater than or equal to 0.75 D was 40%. Conclusion: The prevalence of refractive errors, by the spherical equivalent, was 42.4% in this studied group.