Update on therapy of chronic heart failure. Innovations and studies from last year

被引:1
作者
Ewen, Sebastian [1 ]
Linicus, Y. [1 ]
Boehm, M. [1 ]
机构
[1] Univ Klinikum Saarlandes, Innere Med Klin 3, Kardiol Angiol & Internist Intens Med, D-66421 Homburg, Germany
关键词
European Society of Cardiology guidelines; Acute and chronic heart failure; Bendopnea; Pharmacological therapy; Comorbidity; MINERALOCORTICOID RECEPTOR ANTAGONIST; SODIUM ZIRCONIUM CYCLOSILICATE; PRESERVED EJECTION FRACTION; ATRIAL-FIBRILLATION; CONTROLLED-TRIAL; RENAL-FUNCTION; DOUBLE-BLIND; HYPERKALEMIA; OUTCOMES; ASSOCIATION;
D O I
10.1007/s00059-015-4334-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic heart failure is one of the most common chronic diseases worldwide with increasing prevalence and incidence. Due to the high morbidity and mortality a standardized and evidence-based therapy is crucial. The present review article gives an overview about the innovations in 2014 based on the current guidelines of the European Society of Cardiology. First, improvements in established medication regimens regarding beta blockers and mineralocorticoid receptor antagonists as well as treatment options for heart rate reduction will be explained. Second, new pharmacological developments, such as angiotensin receptor neprilysin inhibition will be discussed. Finally, new insights into common comorbidities of patients with chronic heart failure, such as atrial fibrillation and hyperkalemia will be presented.
引用
收藏
页码:1084 / 1089
页数:6
相关论文
共 33 条
  • [1] New-onset Atrial Fibrillation Predicts Heart Failure Progression
    Aleong, Ryan G.
    Sauer, William H.
    Davis, Gordon
    Bristow, Michael R.
    [J]. AMERICAN JOURNAL OF MEDICINE, 2014, 127 (10) : 963 - 971
  • [2] Relationship between heart rate and mortality and morbidity in the irbesartan patients with heart failure and preserved systolic function trial (I-Preserve)
    Boehm, Michael
    Perez, Ana-Cristina
    Jhund, Pardeep S.
    Reil, Jan C.
    Komajda, Michel
    Zile, Michael R.
    McKelvie, Robert S.
    Anand, Inder S.
    Massie, Barry M.
    Carson, Peter E.
    McMurray, John J. V.
    [J]. EUROPEAN JOURNAL OF HEART FAILURE, 2014, 16 (07) : 778 - 787
  • [3] Böhm M, 2010, LANCET, V376, P886, DOI 10.1016/S0140-6736(10)61259-7
  • [4] Association of Heart Rate and Outcomes in a Broad Spectrum of Patients With Chronic Heart Failure
    Castagno, Davide
    Skali, Hicham
    Takeuchi, Madoka
    Swedberg, Karl
    Yusuf, Salim
    Granger, Christopher B.
    Michelson, Eric L.
    Pfeffer, Marc A.
    McMurray, John J. V.
    Solomon, Scott D.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 59 (20) : 1785 - +
  • [5] Atrial Fibrillation and Mortality in Heart Failure A Community Study
    Chamberlain, Alanna M.
    Redfield, Margaret M.
    Alonso, Alvaro
    Weston, Susan A.
    Roger, Veronique L.
    [J]. CIRCULATION-HEART FAILURE, 2011, 4 (06) : 740 - 746
  • [6] Conduct of Clinical Trials in Acute Heart Failure: Regional Differences in Heart Failure Clinical Trials
    Fiuzat, Mona
    Califf, Robert M.
    [J]. HEART FAILURE CLINICS, 2011, 7 (04) : 539 - +
  • [7] Optimization of pharmacotherapy in chronic heart failure: is heart rate adequately addressed?
    Franke, Jennifer
    Wolter, Jan Sebastian
    Meme, Lillian
    Keppler, Jeannette
    Tschierschke, Ramon
    Katus, Hugo A.
    Zugck, Christian
    [J]. CLINICAL RESEARCH IN CARDIOLOGY, 2013, 102 (01) : 23 - 31
  • [8] Effect of Sodium Zirconium Cyclosilicate on Potassium Lowering for 28 Days Among Outpatients With Hyperkalemia The HARMONIZE Randomized Clinical Trial
    Kosiborod, Mikhail
    Rasmussen, Henrik S.
    Lavin, Philip
    Qunibi, Wajeh Y.
    Spinowitz, Bruce
    Packham, David
    Roger, Simon D.
    Yang, Alex
    Lerma, Edgar
    Singh, Bhupinder
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 312 (21): : 2223 - 2233
  • [9] Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis
    Kotecha, Dipak
    Holmes, Jane
    Krum, Henry
    Altman, Douglas G.
    Manzano, Luis
    Cleland, John G. F.
    Lip, Gregory Y. H.
    Coats, Andrew J. S.
    Andersson, Bert
    Kirchhof, Paulus
    von Lueder, Thomas G.
    Wedel, Hans
    Rosano, Giuseppe
    Shibata, Marcelo C.
    Rigby, Alan
    Flather, Marcus D.
    [J]. LANCET, 2014, 384 (9961) : 2235 - 2243
  • [10] Heart rate is associated with increased risk of major cardiovascular events, cardiovascular and all-cause death in patients with stable chronic cardiovascular disease: an analysis of ONTARGET/TRANSCEND
    Lonn, Eva M.
    Rambihar, Sherryn
    Gao, Peggy
    Custodis, Florian F.
    Sliwa, Karen
    Teo, Koon K.
    Yusuf, Salim
    Boehm, Michael
    [J]. CLINICAL RESEARCH IN CARDIOLOGY, 2014, 103 (02) : 149 - 159