Gold-Catalyzed Cyclization-Cycloaddition Cascade Reactions of Allenyl Acetals with Nitrones

被引：12

作者：

Vasu, Dhananjayan ^{[1
]}

Liu, Rai-Shung ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 43期

关键词：

allenes; 3+2]-cycloaddition; gold; homogeneous catalysis; nitrones; STEREOSELECTIVE-SYNTHESIS; FRAMEWORK; FULVENES; ALKENES; TRICYCLOPENTANOIDS; VINYLIDENES; GENERATION; KETONES;

D O I：

10.1002/chem.201201777

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gold and silver: When allenyl acetals and nitrones are treated with a catalytic amount of a gold complex and a silver salt they react through a cyclization-cycloaddition cascade reaction to give a mixture of diastereomeric tricyclic products. The mixture converges to a single product upon acid hydrolysis (see scheme). The key intermediate is postulated to be a 1-methoxyfulvene species. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：13638 / 13641

页数：4

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