A simple and efficient approach for the palladium-catalyzed ligand-free Suzuki reaction in water

被引：102

作者：

Liu, Chun ^{[1
]}

Zhang, Yixia ^{[1
]}

Liu, Ning ^{[1
]}

Qiu, Jieshan ^{[1
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China

来源：

GREEN CHEMISTRY | 2012年 / 14卷 / 11期

基金：

中国国家自然科学基金;

关键词：

CROSS-COUPLING REACTIONS; LINKED AMPHIPHILIC POLYMER; ARYL CHLORIDES; ARYLBORONIC ACIDS; MIYAURA REACTION; AQUEOUS-MEDIA; GREEN CHEMISTRY; PURE WATER; ASSEMBLED COMPLEX; NANOPARTICLES;

D O I：

10.1039/c2gc36098e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A general and efficient protocol is described for the palladium-catalyzed ligand-free and aerobic Suzuki reaction in water in the absence of any additive. The results demonstrate that the base played a crucial role in the high efficiency. The Pd(OAc)(2)/(i-Pr)(2)NH/H2O system showed the highest catalytic activity towards the Suzuki reaction of a wide range of aryl halides bearing hydrophilic or hydrophobic groups.

引用

页码：2999 / 3003

页数：5

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