A general intramolecular Friedel-Crafts approach to functionalized pyrrolo[3,2,1-ij]quinolin-4-ones

被引：18

作者：

Patil, Dadasaheb V. ^{[1
]}

Cavitt, Marchello A. ^{[1
]}

Grzybowski, Paul ^{[1
]}

France, Stefan ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 83期

基金：

美国国家科学基金会;

关键词：

EFFICIENT SYNTHESIS; DERIVATIVES; ALKYLATION; CYCLIZATION;

D O I：

10.1039/c2cc34650h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An indium(III)-catalyzed intramolecular Friedel-Crafts annulation for the efficient synthesis of pyrrolo[3,2,1-ij]quinolin-4-ones is described. The products are formed in good to excellent yields (51-97%) with diastereoselectivities up to >99 : 1 dr.

引用

页码：10337 / 10339

页数：3

共 33 条

[31] A DCM-type red-fluorescent dopant for high-performance organic electroluminescent devices
Yao, Yi-Shan
Zhou, Qian-Xiong
Wang, Xue-Song
Wang, Yue
Zhang, Bao-Wen
[J]. ADVANCED FUNCTIONAL MATERIALS, 2007, 17 (01) : 93 - 100
[32] Synthesis of methyl 4-methyl-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-6-carboxylate
Zhuravleva, Yu. A.
Zimichev, A. V.
Zemtsova, M. N.
Klimochkin, Yu. N.
[J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 47 (04) : 617 - 618
[33] Ring transformations of heterocyclic compounds.: XXIV [1].: 1′,2′, 5′,6′-tetrahydro-4′H-spiro[cyclohexa-2,4-diene-1,2′-pyrrolo[3,2,1-ij]quinoline] and 1,2,4,5,6,7-hexahydrospiro[azepino[3,2,1-hi]indole-2,1′-cyclo-hexa[2,4]diene] -: Two new spiro [cyclohexadiene-azaheterocycles] easily accessible by pyrylium ring transformation
Zimmermann, T
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (05) : 691 - 695

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