Photosensitivity in the Elderly-Think of Late-Onset Protoporphyria

被引：5

作者：

Frank, Jorge ^{[1
,2
]}

Poblete-Gutierrez, Pamela ^{[3
]}

Neumann, Norbert J. ^{[1
,2
]}

机构：

[1] Univ Dusseldorf, Dept Dermatol, D-40225 Dusseldorf, Germany

[2] Univ Dusseldorf, Porphyria Specialist Ctr, D-40225 Dusseldorf, Germany

[3] Annadal Med Ctr Maastricht, Dept Dermatol, Maastricht, Netherlands

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2013年 / 133卷 / 06期

关键词：

ERYTHROPOIETIC PROTOPORPHYRIA; PHOTODERMATOSES; PORPHYRIAS; DIAGNOSIS; GENE;

D O I：

10.1038/jid.2013.80

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Photosensitivity is the clinical hallmark of both erythropoietic protoporphyria (EPP) and X-linked dominant protoporphyria (XLDPP). Both disorders result from a hereditary dysfunction in heme biosynthesis. Disease onset is usually in early childhood. However, rare patients with late-onset EPP in association with a myeloproliferative disorder or myelodysplastic syndrome have been reported. In this issue, Livideanu et al. describe the first patient with late-onset XLDPP.

引用

页码：1467 / 1471

页数：6

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