Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-Dependent Manner

被引：0
|
作者：
Legleiter, Justin [1 ]
Muchowski, Paul J. [2 ]
机构：
[1] W Virginia Univ, Morgantown, WV 26506 USA
[2] Gladstone Inst Neurol Dis, San Francisco, CA USA
来源：
BIOPHYSICAL JOURNAL | 2010年 / 98卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2009.12.2483
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：457A / 457A
页数：1
相关论文
共 50 条
  • [41] Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner
    Yang, Jiahui
    Freudenreich, Catherine H.
    GENE, 2007, 393 (1-2) : 110 - 115
  • [42] PolyQ-expanded ataxin-3 interacts with full-length ataxin-3 in a polyQ length-dependent manner
    Jia N.-L.
    Fei E.-K.
    Ying Z.
    Wang H.-F.
    Wang G.-H.
    Neuroscience Bulletin, 2008, 24 (4) : 201 - 208
  • [43] Small N-terminal mutant huntingtin fragments, but not wild type, are mainly present in monomeric form: Implications for pathogenesis
    Cong, Shu-Yan
    Pepers, Barry A.
    Roos, Raymund A. C.
    van Ommen, Gert-Jan B.
    Dorsman, Josephine C.
    EXPERIMENTAL NEUROLOGY, 2006, 199 (02) : 257 - 264
  • [44] Fragments of HdhQ150 Mutant Huntingtin Form a Soluble Oligomer Pool That Declines with Aggregate Deposition upon Aging
    Marcellin, David
    Abramowski, Dorothee
    Young, Douglas
    Richter, Jens
    Weiss, Andreas
    Marcel, Audrey
    Maassen, Julia
    Kauffmann, Muriel
    Bibel, Miriam
    Shimshek, Derya R.
    Faull, Richard L. M.
    Bates, Gillian P.
    Kuhn, Rainer R.
    Van der Putten, P. Herman
    Schmid, Peter
    Lotz, Gregor P.
    PLOS ONE, 2012, 7 (09):
  • [45] Translational regulation of hepatitis B virus polymerase gene by termination-reinitiation of an upstream minicistron in a length-dependent manner
    Hwang, WL
    Su, TS
    JOURNAL OF GENERAL VIROLOGY, 1998, 79 : 2181 - 2189
  • [46] Short RNA Duplexes Elicit RIG-I-Mediated Apoptosis in a Cell Type-and Length-Dependent Manner
    Ishibashi, Osamu
    Ali, Md. Moksed
    Luo, Shan-Shun
    Ohba, Takashi
    Katabuchi, Hidetaka
    Takeshita, Toshiyuki
    Takizawa, Toshihiro
    SCIENCE SIGNALING, 2011, 4 (198)
  • [47] Mutant huntingtin affects p53 function in a context-dependent manner in a cell model of Huntington's disease
    Ellison, Genevieve A.
    Garcia, Loren S.
    Cornett, Jonathan C.
    FASEB JOURNAL, 2018, 32 (01):
  • [48] Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: Implications for protein-induced membrane fusion
    Siegel, DP
    Cherezov, V
    Greathouse, DV
    Koeppe, RE
    Killian, JA
    Caffrey, M
    BIOPHYSICAL JOURNAL, 2006, 90 (01) : 200 - 211
  • [49] Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
    Lee, Youn-Bok
    Chen, Han-Jou
    Peres, Joao N.
    Gomez-Deza, Jorge
    Attig, Jan
    Stalekar, Maja
    Troakes, Claire
    Nishimura, Agnes L.
    Scotter, Emma L.
    Vance, Caroline
    Adachi, Yoshitsugu
    Sardone, Valentina
    Miller, Jack W.
    Smith, Bradley N.
    Gallo, Jean-Marc
    Ule, Jernej
    Hirth, Frank
    Rogelj, Boris
    Houart, Corinne
    Shaw, Christopher E.
    CELL REPORTS, 2013, 5 (05): : 1178 - 1186
  • [50] Very-long-chain aldehydes promote in vitro prepenetration processes of Blumeria graminis in a dose- and chain length-dependent manner
    Hansjakob, Anton
    Bischof, Sebastian
    Bringmann, Gerhard
    Riederer, Markus
    Hildebrandt, Ulrich
    NEW PHYTOLOGIST, 2010, 188 (04) : 1039 - 1054
12345