Adaptive neuro fuzzy selection of heart rate variability parameters affected by autonomic nervous system

Heart rate variability (HRV) parameters can be used as specific indicator of autonomic nervous system (ANS) behavior. ANS, with its main two branches, sympathetic and parasympathetic, may be considered as a coordinated neuronal network which controls heart rate continually. Many parameters define heart rate variability in different domains such as time, frequency or nonlinear. An excessively high computational complexity can occur when developing models for medical applications when the best set of inputs to use is not known. To build a model that can predict a specific process output, it is desirable to select a subset of variables that are truly relevant or the most influential to this output. This procedure is typically called variable selection, and it corresponds to finding a subset of the full set of recorded variables that exhibits good predictive abilities. In this study an architecture for modeling complex systems in function approximation and regression was used, based on using adaptive neuro-fuzzy inference system (ANFIS). Variable searching using the ANFIS network was performed to determine how the ANS branches affect the most relevant HRV parameters. The method utilized may work as a basis for examination of ANS influence on HRV activity. (C) 2013 Elsevier Ltd. All rights reserved.